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Seminars

During the academic year, we sponsor a seminar on most Mondays at 4:00 PM, in the Lecture Hall (E501). We pride ourselves on presenting, at almost every seminar, an eminent scholar from around the country or around the globe.

Upcoming Seminars


Elizabeth G. Damato, PhD, RN, APRN
Elizabeth G. Damato, PhD, RN, APRN
Case Western Reserve University
Aug. 24, 2022 1 p.m. - 2 p.m.
School of Medicine E501
Hosted by: Michael J. Decker, PhD

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DEPARTMENT SPECIAL SEMINAR

"Increased serum levels of proinflammatory cytokines and fatigue emerge in aviators following repetitive exposure to aggressive flight maneuvers"


Xiaochun Li, PhD
Xiaochun Li, PhD
University of Texas Southwestern Medical Center
Sept. 19, 2022 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Nami Tajima

View Seminar >

DEPARTMENT SEMINAR

"Molecular basis of membrane-bound O-acyltransferases in cholesterol metabolism and Wnt lipidation  "


Sichen (Susan) Shao, PhD
Sichen (Susan) Shao, PhD
Harvard Medical School
Sept. 26, 2022 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

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DEPARTMENT SEMINAR

"Corrective protein quality control prevents wasteful ER-associated degradation"


Tija C. Jacob, PhD
Tija C. Jacob, PhD
University of Pittsburgh School of Medicine
Oct. 10, 2022 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"Yin-yang imbalance: drug-induced neuroplasticity of inhibitory and excitatory synapses"


Roger A. Nicoll, MD
Roger A. Nicoll, MD
University of California – San Francisco School of Medicine
Oct. 12, 2022 4 p.m. - 5 p.m.
School of Medicine 5th floor Bridge
Hosted by: Nami Tajima, PhD

View Seminar >

FRONTIERS IN BIOLOGICAL SCIENCES LECTURE

"TBA"


Heath Gasier, PhD
Heath Gasier, PhD
Duke University School of Medicine
Nov. 14, 2022 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Rossana Occhipinti, PhD

View Seminar >

DEPARTMENT SEMINAR

"GABA transporter inhibition attenuates oxidative tissue injury in the cerebellum and hippocampus of mice exposed to extreme hyperbaric oxygen"


Anne E. Carlson, PhD
Anne E. Carlson, PhD
University of Pittsburgh
Dec. 5, 2022 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"TBA"


Recent Seminars


Megan Wang, PhD
Megan Wang, PhD
Case Western Reserve University
Aug. 5, 2022 1 p.m. - 2 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SPECIAL SEMINAR

"Mapping Protein Homeostasis Network for a Membrane Protein"


Jeffrey R. Schelling, MD
Jeffrey R. Schelling, MD
MetroHealth Medical Center / Case Western Reserve University School of Medicine
June 28, 2022 10 a.m. - 11 a.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SPECIAL SEMINAR

"FATP2-Mediated Lipotoxicity in the Pathophysiology of Diabetic Kidney Disease"


Oleg Klykov, PhD
Oleg Klykov, PhD
New York Structural Biology Center
May 10, 2022 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SPECIAL SEMINAR

"High-resolution in-situ cryo-ET approaches to study Membrane Protein Complexes"


Wayland W. L. Cheng, MD, PhD
Wayland W. L. Cheng, MD, PhD
Washington University in St. Louis
May 2, 2022 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"Mechanisms of Lipid Modulation of Ligand-Gated Ion Channels"


Xiao Heng, PhD
Xiao Heng, PhD
University of Missouri College of Agriculture, Food and Natural Resources
April 25, 2022 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Xinghong Dai, PhD

View Seminar >

DEPARTMENT SEMINAR

"Beyond reverse transcription initiation -- Structure and function characterization of HIV-1 primer binding site"


Robert Harvey, PhD
Robert Harvey, PhD
University of Nevada - Reno School of Medicine
April 18, 2022 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Corey Smith, PhD

View Seminar >

DEPARTMENT SEMINAR

"Cyclic AMP Signaling: Ubiquitous and Complex"


David W. Piston, PhD
David W. Piston, PhD
Washington University School of Medicine in St. Louis
April 11, 2022 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

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DEPARTMENT SEMINAR

"Adventures in Glucagon, the Other Islet Hormone"


Maj. Jackson "Slick" Martin
Maj. Jackson "Slick" Martin
United States Air Force
April 5, 2022 10 a.m. - noon
School of Medicine E501
Hosted by: Michael J. Decker, PhD

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SPECIAL LECTURE

"Physiologic lessons learned while piloting the F35"


Dominic P. D'Agostino, PhD
Dominic P. D'Agostino, PhD
University of South Florida Morsani School of Medicine / Florida Institute for Human and Machine Cognition
POSTPONED
April 4, 2022 4 p.m. - 5 p.m.

School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

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DEPARTMENT SEMINAR

"The Science and Application of Therapeutic Ketosis"


Alexander Mazin, PhD
Alexander Mazin, PhD
University of Texas Health Science Center - San Antonio, Long School of Medicine
March 21, 2022 4 p.m. - 5 p.m.
Remotely via Zoom
Hosted by: Xinghong Dai, PhD

View Seminar >

DEPARTMENT SEMINAR

"RAD52 and RPA in DNA repair: Focus on RNA"


Shrawan Kumar Mageswaran, PhD
Shrawan Kumar Mageswaran, PhD
Perelman School of Medicine, University of Pennsylvania
March 15, 2022 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

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DEPARTMENT SPECIAL SEMINAR

"In situ cryo-electron tomography to study membrane remodeling systems"


Yamuna Krishnan, PhD
Yamuna Krishnan, PhD
University of Chicago
March 14, 2022 4 p.m. - 5 p.m.
Remotely only via Zoom
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"Quantitative Chemical Imaging of Organelles"


Shiwei Zhu, PhD
Shiwei Zhu, PhD
Yale School of Medicine
March 8, 2022 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SPECIAL SEMINAR

"Cryo-ET Pipeline for Imaging Small Proteins in Large Biological Structures"


Matthias Kretzler, MD
Matthias Kretzler, MD
University of Michigan Medical School
March 7, 2022 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

ULRICH HOPFER LECTURE

"Defining Nephron Function and Failure across continents and disciplines"


Xiaojie Zhang, PhD
Xiaojie Zhang, PhD
European Molecular Biology Laboratory / Heidelberg, Germany
March 3, 2022 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SPECIAL SEMINAR

"Expect the unexpected in cellular cryo-electron tomography: molecular basis of stress-induced mumps virus reactivation"


Muyuan Chen, PhD
Muyuan Chen, PhD
Baylor College of Medicine
March 1, 2022 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

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DEPARTMENT SPECIAL SEMINAR

"Explore the complexity of macromolecular structures using Cryo-electron tomography"


Shyamal Mosalaganti, PhD
Shyamal Mosalaganti, PhD
University of Michigan Medical School
Feb. 28, 2022 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"Structural Biology in-situ"


Christopher (Chris) Gillen, PhD
Christopher (Chris) Gillen, PhD
Kenyon College
POSTPONED
Feb. 21, 2022 4 p.m. - 5 p.m.

School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SEMINAR

"Novel sodium-dependent cation-chloride cotransporters in insects"


Archived Seminars


Tianmin Fu, PhD
Tianmin Fu, PhD
The Ohio State University College of Medicine
Feb. 14, 2022 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Xinghong Dai, PhD

View Seminar >

DEPARTMENT SEMINAR

"It takes two to tango: mechanisms of lysosomal pH homeostasis"


Jeffrey L. Ardell, PhD
Jeffrey L. Ardell, PhD
University of California -Los Angeles School of Medicine
Feb. 7, 2022 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Corey Smith, PhD

View Seminar >

DEPARTMENT SEMINAR

"Bioelectric therapy: Clinical applications for cardiac disease"


Ardeschir Vahedi-Faridi, PhD
Ardeschir Vahedi-Faridi, PhD
Case Western Reserve University
Jan. 10, 2022 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SPECIAL SEMINAR

"Functional diversity of Channel Proteins" a hybrid Electron microscopic and X-ray crystallographic approach"


Lonnie P. Wollmuth, PhD
Lonnie P. Wollmuth, PhD
Stony Brook University (SUNY)
Nov. 15, 2021 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Nami Tajima

View Seminar >

DEPARTMENT SEMINAR

"Fast signaling via the NMDA receptor"


Crina Nimigean, PhD
Crina Nimigean, PhD
Cornell University Medical College / Weill Cornell Medicine
Nov. 1, 2021 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"Gating and ball-and-chain inactivation in a calcium-gated potassium channel"


Howard A. Rockman, MD
Howard A. Rockman, MD
Duke University School of Medicine
Oct. 28, 2021 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

6TH ANNUAL MATTHEW N. LEVY LECTURE

"Beta-Adrenergic Receptor Signaling:  Evolving Concepts and Therapeutics"


Ming Zhou, PhD
Ming Zhou, PhD
Baylor College of Medicine
Oct. 25, 2021 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Nami Tajima, PhD

View Seminar >

DEPARTMENT SEMINAR

"Mechanism of iron transport in human ferroportin"


Erkan Karakas, PhD
Erkan Karakas, PhD
Vanderbilt University School of Medicine
Oct. 11, 2021 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Nami Tajima

View Seminar >

DEPARTMENT SEMINAR

"Structural characterization of IP3 receptor calcium channels by cryo-EM"


Michael F. Romero, PhD
Michael F. Romero, PhD
Mayo Clinic College of Medicine
Sept. 27, 2021 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SEMINAR

"Insights into kidney stones through radical nephrectomy in fruit flies"


J. Benita Sjögren, PhD
J. Benita Sjögren, PhD
Purdue University College of Pharmacy
Sept. 20, 2021 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Patrick Osei-Owusu, PhD, FAHA

View Seminar >

DEPARTMENT SEMINAR

"Mechanisms of RGS protein regulation in health and disease"


Jay Dean, PhD
Jay Dean, PhD
University of South Florida Morsani College of Medicine
Sept. 13, 2021 noon - 1 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SEMINAR

"CNS oxygen toxicity: where are we now?"


Ole Mortensen, PhD
Ole Mortensen, PhD
Drexel University College of Medicine
May 10, 2021 4 p.m. - 5 p.m.
Remotely via Zoom
Hosted by: Patrick Osei-Owusu, PhD, FAHA

View Seminar >

DEPARTMENT SEMINAR

"Allosteric modulation of monoamine transporters as a therapeutic target for drug addiction"


John R. Sedor, MD
John R. Sedor, MD
Cleveland Clinic Foundation Lerner Research Institute / Lerner College of Medicine (CWRU/CCF)
April 26, 2021 4 p.m. - 5 p.m.
Remotely via Zoom
Hosted by: Jeffrey L. Garvin, PhD

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DEPARTMENT SEMINAR

"APOL1 & the Pandemic Year: Race, Ancestry & COVID-19"


Ranajeet Ghose, PhD
Ranajeet Ghose, PhD
The Graduate Center - City University of New York
April 19, 2021 4 p.m. - 5 p.m. None Hosted by: Matthias Buck

View Seminar >

DEPARTMENT SEMINAR

"Activation and regulation of a family of tyrosine kinases unique to bacteria"


Irving H. Zucker, PhD, FAHA, FAPS
Irving H. Zucker, PhD, FAHA, FAPS
University of Nebraska Medical Center College of Medicine
April 12, 2021 4 p.m. - 5 p.m.
Remotely via Zoom
Hosted by: Mark E. Dunlap, MD

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DEPARTMENT SEMINAR

"Mechanisms of Central Oxidant Stress and the Regulation of Sympathetic Nerve Activity: Implications for Cardiovascular Disease"


Ben W. Strowbridge, PhD
Ben W. Strowbridge, PhD
Case Western Reserve University
April 5, 2021 4 p.m. - 5 p.m.
Remotely via Zoom
Hosted by: Corey Smith, PhD

View Seminar >

DEPARTMENT SEMINAR

"Cellular mechanisms of persistent activity and mnemonic representations in cortical brain regions"


Angelo Keramidas, PhD
Angelo Keramidas, PhD
University of Queensland
March 29, 2021 4 p.m. - 5 p.m.
Remotely via Zoom
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"Disease-causing synaptic receptor variants"


Linda  Columbus, PhD
Linda Columbus, PhD
University of Virginia
March 22, 2021 4 p.m. - 5 p.m.
Remotely via Zoom
Hosted by: Matthias Buck

View Seminar >

DEPARTMENT SEMINAR

"From lipid/detergent - protein interactions to host - pathogen interactions, how do (some) membrane proteins work?"


Qiuye Li, PhD
Qiuye Li, PhD
Case Western Reserve University
March 8, 2021
Remotely via Zoom
Hosted by: Witold K. Surewicz, PhD

View Seminar >

DEPARTMENT SEMINAR

"Cryo-EM structure of amyloid fibrils formed by the entire low complexity domain of TDP-43"


Gustav Akk, PhD
Gustav Akk, PhD
Washington University School of Medicine in St. Louis
March 1, 2021 4 p.m. - 5 p.m.
Remotely via Zoom
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"Activation of the GABA-A receptor by combinations of orthosteric and allosteric agonists"


Lalit Deshmukh, PhD
Lalit Deshmukh, PhD
University of California - San Diego
Feb. 22, 2021 4 p.m. - 5 p.m.
Remotely via Zoom
Hosted by: Sichun Yang, PhD

View Seminar >

DEPARTMENT SEMINAR

"ALIX in Wonderland: Multivalency, Phosphorylation-mediated Amyloids, Autoinhibition, and Endosomal Membrane Interactions"


Abhishek   A. Chakraborty, PhD
Abhishek A. Chakraborty, PhD
Lerner College of Medicine (CWRU) / Lerner Research Institute / Cleveland Clinic Foundation
Feb. 15, 2021 4 p.m. - 5 p.m.
Remotely via Zoom
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"Dioxygenase Dysfunction Presents Therapeutically Targetable Vulnerabilities in Cancer"


Xin Zhang, PhD
Xin Zhang, PhD
Penn State Eberly College of Science
Feb. 8, 2021 4 p.m. - 5 p.m.
Remotely via Zoom
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"Chemical Biology of Protein Aggregation in Membraneless Organelles and the Stressed Proteome"


Joongkyu Park, PhD
Joongkyu Park, PhD
Wayne State University School of Medicine
Feb. 1, 2021 4 p.m. - 5 p.m.
Remotely via Zoom
Hosted by: Nami Tajima, PhD

View Seminar >

DEPARTMENT SEMINAR

"Molecular mechanisms of fear learning in mice and beyond"


W. Jonathan Lederer, MD, PhD
W. Jonathan Lederer, MD, PhD
University of Maryland School of Medicine
Dec. 7, 2020 4 p.m. - 5 p.m.
Remotely via Zoom
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SEMINAR

"ATP Production in Heart by Mitochondria"


J. Michelle Kahlenberg, MD, PhD
J. Michelle Kahlenberg, MD, PhD
University of Michigan Medical School
Nov. 30, 2020 4 p.m. - 5 p.m.
Remotely via Zoom
Hosted by: George R. Dubyak, PhD

View Seminar >

DEPARTMENT SEMINAR

"Outside In: Understanding Lupus Pathogenesis In the Skin"


Teresa Giráldez Fernández, PhD
Teresa Giráldez Fernández, PhD
Universidad de La Laguna (Tenerife, Spain)
Nov. 16, 2020 1 p.m. - 2 p.m.
Remotely via Zoom
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR POSTPONED

"Structural rearrangements underlying the function of BK channels"


Adebowale (Ade)  Adebiyi, PhD
Adebowale (Ade) Adebiyi, PhD
University of Tennessee Health Science Center
Nov. 9, 2020 4 p.m. - 5 p.m.
Remotely via Zoom
Hosted by: Patrick Osei-Owusu, PhD, FAHA

View Seminar >

DEPARTMENT SEMINAR

"Regulation of neonatal renal microcirculation"


Xianfang Wu, PhD
Xianfang Wu, PhD
Lerner Research Institute - Cleveland Clinic Foundation
Nov. 2, 2020 4 p.m. - 5 p.m.
Remotely via Zoom
Hosted by: Xinghong Dai, PhD

View Seminar >

DEPARTMENT SEMINAR

"Modeling human diseases: how pluripotency helps?"


Michael F. Romero, PhD
Michael F. Romero, PhD
Mayo Clinic College of Medicine
Oct. 26, 2020 4 p.m. - 5 p.m.
Remotely via Zoom
Hosted by: Rossana Occhipinti, PhD

View Seminar >

DEPARTMENT SEMINAR

"Acidosis, cysts, glaucoma and diabetes - Who needs to transport baking soda (NaHCO3) anyway?"


Allison Kraus, PhD
Allison Kraus, PhD
Case Western Reserve University
Oct. 19, 2020 4 p.m. - 5 p.m.
Remotely via Zoom
Hosted by: Rajesh Ramachandran, PhD

View Seminar >

DEPARTMENT SEMINAR

"Protein seeds of neurodegenerative diseases: Structure and diagnosis"


Eric Delpire, PhD
Eric Delpire, PhD
Vanderbilt University School of Medicine
Oct. 12, 2020 4 p.m. - 5 p.m.
Remotely via Zoom
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SEMINAR

"Human disease causing mutations in SLC12A2, the gene encoding the Na-K-2Cl cotransporter-1"


Harpreet Singh, PhD
Harpreet Singh, PhD
Ohio State University College of Medicine
Oct. 5, 2020 4 p.m. - 5 p.m.
Remotely via Zoom
Hosted by: Patrick Osei-Owusu, PhD, FAHA

View Seminar >

DEPARTMENT SEMINAR

"Intracellular Ion Channels: Identification and Physiological Roles"


Christine N. Metz, PhD
Christine N. Metz, PhD
Feinstein Institutes for Medical Research (Northwell Health) and Zucker School of Medicine at Hofstra/Northwell
April 27, 2020 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Andrea Romani, MD, PhD

View Seminar >

DEPARTMENT SEMINAR POSTPONED

"Magnesium: Role in Cisplatin-Induced Acute Kidney Injury and Cancer Cell Biology"


Roger A. Nicoll, MD
Roger A. Nicoll, MD
University of California – San Francisco School of Medicine
April 15, 2020 4 p.m.
School of Medicine E501
Hosted by:

View Seminar >

FRONTIERS IN BIOLOGICAL SCIENCES LECTURE POSTPONED FROM APRIL 15

"In search of the molecules of memory"


Eugenia Trushina, PhD
Eugenia Trushina, PhD
Mayo Clinic
April 6, 2020 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Xin Qi, PhD

View Seminar >

DEPARTMENT SEMINAR POSTPONED

"Partial inhibition of mitochondrial complex I as a therapeutic strategy for neurodegenerative diseases"


Anthony W. P. Fitzpatrick, PhD
Anthony W. P. Fitzpatrick, PhD
Columbia University
March 9, 2020 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Xinghong Dai, PhD

View Seminar >

DEPARTMENT SEMINAR CANCELED

"TBA"


Robert M. Carey, MD, MACP
Robert M. Carey, MD, MACP
University of Virginia School of Medicine
March 2, 2020
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

8TH ANNUAL ULRICH HOPFER LECTURE

"Defective renal AT2 receptor signaling in hypertension"


Virginia H. Huxley, PhD
Virginia H. Huxley, PhD
University of Missouri School of Medicine - Columbia
Feb. 24, 2020 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Rossana Occhipinti, PhD

View Seminar >

DEPARTMENT SEMINAR

"Contribution of Sex to Endothelial Heterogeneity from Message to Function"


Elizabeth G. Damato, PhD, RN, APRN
Elizabeth G. Damato, PhD, RN, APRN
Case Western Reserve University
Feb. 13, 2020 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

View Seminar >

DCAPT SEMINAR

"The Impact of Hyperoxia: A Systems Physiology Approach"


Matthew D. Shoulders, PhD
Matthew D. Shoulders, PhD
Massachusetts Institute of Technology
Feb. 10, 2020 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"Proteostasis, Evolution, and Pathogens"


R. Luke Wiseman, PhD
R. Luke Wiseman, PhD
Scripps Research
Feb. 3, 2020 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Xin Qi, PhD

View Seminar >

DEPARTMENT SEMINAR

"A Little Goes a Long Way: Pharmacologically Targeting the Unfolded Protein Response for Etiologically Diverse Diseases "


Rui Zhang, PhD
Rui Zhang, PhD
Washington University in St. Louis
Jan. 27, 2020 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Xinghong Dai, PhD

View Seminar >

DEPARTMENT SEMINAR

"High-resolution cryo-EM structure of a natively decorated doublet microtubule "


D. S. Fahmeed Hyder, PhD
D. S. Fahmeed Hyder, PhD
Yale University Schools of Medicine and Engineering & Applied Sciences
Jan. 13, 2020 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SEMINAR

"Imaging the transmembrane gradients for hydrogen and sodium ions "


William N. Green, PhD
William N. Green, PhD
University of Chicago
Dec. 9, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"How nicotine and synaptic activity change the Golgi apparatus "


Lillian T. Chong, PhD
Lillian T. Chong, PhD
University of Pittsburgh
Dec. 2, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Matthias Buck

View Seminar >

DEPARTMENT SEMINAR

"The ‘Art of Possibility’: Weighted Ensemble of Trajectories "


Ayyalusamy ("Rams") Ramamoorthy, PhD
Ayyalusamy ("Rams") Ramamoorthy, PhD
University of Michigan
Nov. 25, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"Probing Dynamic Protein-Protein Interactions in a Membrane Environment by NMR "


Susumu  Tomita, PhD
Susumu Tomita, PhD
Yale University School of Medicine
Nov. 18, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"Molecular machinery for synaptic transmission "


Filip L. A. Van Petegem, PhD
Filip L. A. Van Petegem, PhD
University of British Columbia Faculty of Medicine
Nov. 11, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Rajendra (Venkata) Boggavarapu, PhD

View Seminar >

DEPARTMENT SEMINAR

"Cardiac arrhythmias and muscle disorders: crystallographic and cryo-EM insights into channelopathies "


Zhaozhu Qiu, PhD
Zhaozhu Qiu, PhD
Johns Hopkins University School of Medicine
Nov. 4, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Xinghong Dai, PhD

View Seminar >

DEPARTMENT SEMINAR

"From SWELL to PAC: Discovery of New Ion Channels "


Leslie Leinwand, PhD, FAHA
Leslie Leinwand, PhD, FAHA
University of Colorado
Oct. 31, 2019 1:30 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

5TH ANNUAL MATTHEW N. LEVY LECTURE

"Myosin myopathies: mechanisms of pathogenesis and paths to therapeutics "


Xiaochen Bai, PhD
Xiaochen Bai, PhD
University of Texas Southwestern Medical Center
Oct. 28, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Matthias Buck

View Seminar >

DEPARTMENT SEMINAR

"Cryo-EM analysis of full-length receptor tyrosine kinase "


Tsan Sam Xiao, PhD
Tsan Sam Xiao, PhD
Case Western Reserve University
Oct. 21, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"The cut that makes the difference: mechanisms of gasdermin D-mediated pyroptosis "


Xinnan Wang, MD, PhD
Xinnan Wang, MD, PhD
Stanford University School of Medicine
Oct. 14, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Xin Qi, PhD

View Seminar >

DEPARTMENT SEMINAR

"Targeting Mitochondrial Miro1 for Detecting and Treating Parkinson’s Disease "


Jeanne C. Stachowiak, PhD
Jeanne C. Stachowiak, PhD
University of Texas at Austin
Oct. 7, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Bing-Cheng Wang, PhD

View Seminar >

DEPARTMENT SEMINAR

"Stochastic Mechanisms in Membrane Traffic "


Valeria Vásquez, PhD
Valeria Vásquez, PhD
University of Tennessee Health Science Center
Sept. 30, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

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DEPARTMENT SEMINAR

"Dietary fatty acids fine-tune cells mechanical response "


Ryan W. Bavis, PhD
Ryan W. Bavis, PhD
Bates College
Sept. 23, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Richard J. Martin, MD

View Seminar >

DEPARTMENT SEMINAR

"Oxygen's influence on the maturation of the respiratory control system "


Jiansen Jiang, PhD
Jiansen Jiang, PhD
National Heart, Lung, and Blood Institute (NIH)
Sept. 16, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Xinghong Dai, PhD

View Seminar >

DEPARTMENT SEMINAR

"Pushing the resolution limit of cryoEM for small membrane proteins"


Roshan J. Thapa, MD
Roshan J. Thapa, MD
Baruch S. Blumberg Institute of Living Science
Sept. 9, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Xinghong Dai, PhD

View Seminar >

DEPARTMENT SEMINAR

"STING-Mediated Programmed Cell Death "


Patrick Osei-Owusu, PhD, FAHA
Patrick Osei-Owusu, PhD, FAHA
Drexel University College of Medicine
Aug. 19, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SPECIAL SEMINAR

"Making A Case For A Causal vs. Facilitative Role Of Elastin Deficiency In CKD Pathogenesis "


Jeffrey R. Schelling, MD
Jeffrey R. Schelling, MD
MetroHealth Medical Center / Case Western Reserve University School of Medicine
June 10, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: William P. Schilling, PhD

View Seminar >

DCAPT SEMINAR

"Fatty Acid Transporter-2 (FATP2) in the Pathogenesis of Diabetic Kidney Disease "


Richard W. Pastor, PhD
Richard W. Pastor, PhD
National Heart, Lung, and Blood Institute (NIH)
May 6, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Matthias Buck

View Seminar >

DEPARTMENT SEMINAR

"Molecular Dynamics Simulations of Membrane Permeability "


Jay Dean, PhD
Jay Dean, PhD
University of South Florida Morsani College of Medicine
April 30, 2019 noon
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

CENTER FOR AEROSPACE PHYSIOLOGY INAUGURAL SYMPOSIUM SEMINAR

"Winning the physiological air war of 1939-1945:  the history of aero medical research and practices in America during WW2 "


Aerospace Physiology Symposium
Aerospace Physiology Symposium
Case Western Reserve University
April 29, 2019 8 a.m. - 5 p.m.
Thwing Center — Excelsior Ballroom
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

INAUGURAL SYMPOSIUM FOR THE CENTER FOR AEROSPACE PHYSIOLOGY

"Featured Lecture:  CNS oxygen toxicity in undersea medicine: mechanisms and mitigation strategies "


Albert R. LaSpada, MD, PhD, FACMG
Albert R. LaSpada, MD, PhD, FACMG
Duke University School of Medicine
April 29, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Xin Qi, PhD

View Seminar >

DEPARTMENT SEMINAR

"Convergent pathways in neurodegeneration: From polyglutamine disease targets to broad-based therapeutic opportunities"


Jing-Qiong Kang, MD, PhD
Jing-Qiong Kang, MD, PhD
Vanderbilt University School of Medicine
April 22, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"Pathophysiology of GABAA receptor mutations associated with variable epilepsy syndromes"


C. Michael Crowder, MD, PhD
C. Michael Crowder, MD, PhD
University of Washington
April 15, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Xin Qi, PhD

View Seminar >

DEPARTMENT SEMINAR

"The Translation Machinery Determines Hypoxic Sensitivity"


Cynthia Czajkowski, PhD
Cynthia Czajkowski, PhD
University of Wisconsin - Madison
April 8, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"Detecting ligand induced motions in pentameric ligand-gated ion channels"


Gerhard Hummer, PhD
Gerhard Hummer, PhD
Max Planck Institute for Biophysics
April 5, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Matthias Buck

View Seminar >

DEPARTMENT SPECIAL SEMINAR

"Molecular simulations of membrane sensing, shaping, and remodeling "


Christian Aalkjaer, MD
Christian Aalkjaer, MD
Aarhus University (Denmark)
April 4, 2019 None Hosted by:

View Seminar >

NONE

"Dale test "


Prof. Amitabha Chattopadhyay, PhD
Prof. Amitabha Chattopadhyay, PhD
Centre for Cellular & Molecular Biology
April 3, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Rajesh Ramachandran, PhD

View Seminar >

DEPARTMENT SPECIAL SEMINAR

"Interaction of Membrane Cholesterol with G Protein-Coupled Receptors: Novel Insights in Health & Disease"


Carlos T. Moraes, PhD
Carlos T. Moraes, PhD
Leonard M. Miller School of Medicine - University of Miami
April 1, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"Developing Genetic Treatments for Mitochondrial DNA Diseases"


Adam W. Smith, PhD
Adam W. Smith, PhD
University of Akron (OH)
March 25, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

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DCAPT SEMINAR

"Spatial regulation of receptor tyrosine kinases "


Alicia McDonough, PhD, FAHA
Alicia McDonough, PhD, FAHA
University of Southern California - Keck School of Medicine
March 18, 2019 4 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

7TH ANNUAL ULRICH HOPFER LECTURE

"Maintaining Balance under Pressure: renal adaptations to angiotensin II hypertension in females and males "


Sharona Gordon, PhD
Sharona Gordon, PhD
University of Washington
March 11, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"No gain, no pain: phosphoinositide regulation of TRPV1 ion channels"


Elizabeth G. Damato, PhD, RN, APRN
Elizabeth G. Damato, PhD, RN, APRN
Case Western Reserve University
Feb. 26, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

View Seminar >

DCAPT SEMINAR POSTPONED TBD

"You can never be too rich, too thin, or have too much oxygen...Or can you?? "


Sam Mesiano, PhD
Sam Mesiano, PhD
University Hospitals
Feb. 25, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

View Seminar >

DEPARTMENT SEMINAR

"Exploiting the molecular biology of progesterone to prevent preterm birth"


George B. Richerson, MD, PhD
George B. Richerson, MD, PhD
University of Iowa Carver College of Medicine
Feb. 18, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SEMINAR

"The retrotrapezoid nucleus: A site for chemoreceptors or just a relay for other pH sensors?"


Shirley ShiDu Yan, MD
Shirley ShiDu Yan, MD
University of Kansas School of Pharmacology
Feb. 11, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Xin Qi, PhD

View Seminar >

DEPARTMENT SEMINAR

"Targeting Mitochondria as a Potential Therapeutic Strategy for Alzheimer’s Disease"


Christopher I. Richards, PhD
Christopher I. Richards, PhD
University of Kentucky
Jan. 28, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"Brain region specific single molecule imaging of nicotinic receptors"


Xiaolei Xu, PhD
Xiaolei Xu, PhD
Mayo Clinic
Jan. 14, 2019 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Julian E. Stelzer, PhD

View Seminar >

DEPARTMENT SEMINAR

"Discover New Genes and Therapies for Cardiomyopathy via Zebrafish Genetics"


Michael K. Rosen, PhD
Michael K. Rosen, PhD
University of Texas Southwestern Medical Center
Dec. 17, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

View Seminar >

DEPARTMENT SEMINAR

"Physical Mechanisms of Cell Organization on Micron Length Scales"


Ryan Hibbs, PhD
Ryan Hibbs, PhD
University of Texas Southwestern Medical Center
Dec. 10, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"Architecture and mechanism of pentameric neurotransmitter receptors"


Brett A. Colson, PhD
Brett A. Colson, PhD
University of Arizona
Dec. 3, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Julian E. Stelzer, PhD

View Seminar >

DEPARTMENT SEMINAR

"Myofilament interactions of cardiac myosin-binding protein C N-terminal domains"


Jil C. Tardiff, MD, PhD
Jil C. Tardiff, MD, PhD
University of Arizona College of Medicine - Tucson
Nov. 26, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Ranganath Mamidi, PhD

View Seminar >

DEPARTMENT SEMINAR

"Developing a Fully Integrative Approach to Define the Molecular Pathogenesis of Hypertrophic Cardiomyopath"


Cory Dunn, PhD
Cory Dunn, PhD
University of Helsinki
Nov. 19, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Rajesh Ramachandran, PhD

View Seminar >

DEPARTMENT SEMINAR

"Organelle targeting of tail-anchored proteins"


Joshua S. Chappie, PhD
Joshua S. Chappie, PhD
Cornell University College of Veterinary Medicine
Nov. 12, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Rajesh Ramachandran, PhD

View Seminar >

DEPARTMENT SEMINAR

"Structural characterization of a nucleotide-powered endonuclease complex involved in bacterial defense"


Mark E. Dunlap, MD
Mark E. Dunlap, MD
MetroHealth Medical Center / Case Western Reserve University School of Medicine
Nov. 5, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

View Seminar >

DEPARTMENT SEMINAR

"Autonomic Modulation of Venous Capacitance in the Pathophysiology of Acute HF"


Julio Cordero-Morales, PhD
Julio Cordero-Morales, PhD
University of Tennessee Health Science Center
Oct. 29, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"The Role of Bioactive Lipids in Transient Receptor Potential Channels Function"


Radu Aricescu, PhD
Radu Aricescu, PhD
University of Cambridge
Oct. 24, 2018 4 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

FRONTIERS IN BIOLOGICAL SCIENCES LECTURE

"Human GABAA Receptor Structures and Signaling Mechanisms "


Ardeschir Vahedi-Faridi, PhD
Ardeschir Vahedi-Faridi, PhD
Case Western Reserve University
Oct. 22, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

View Seminar >

DEPARTMENT SEMINAR

"Towards a structural understanding of aquaporin function and activation: a hybrid Electron microscopic and X-ray crystallographic approach"


Wah Chiu, PhD
Wah Chiu, PhD
Stanford University
Oct. 17, 2018 1 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SPECIAL SEMINAR

"Cryo-EM, an imaging tool beyond crystallography"


Peter MacFarlane, PhD
Peter MacFarlane, PhD
Case Western Reserve University / University Hospitals - Rainbow Babies & Children's Hospital
Oct. 15, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

View Seminar >

DEPARTMENT SEMINAR

"Critical windows of respiratory system development - adverse consequences to early life insults"


Gary A.  Lorigan, PhD
Gary A. Lorigan, PhD
Miami University of Ohio
Oct. 8, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"Magnetic Resonance Studies of Membrane Proteins"


Carol Toris, PhD
Carol Toris, PhD
Case Western Reserve University / University Hospitals of Cleveland
Oct. 1, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

View Seminar >

DEPARTMENT SEMINAR

"New ideas in glaucoma therapeutics"


Richard J. Martin, MD
Richard J. Martin, MD
University Hospitals Cleveland Medical Center / Case Western Reserve University School of Medicine
Sept. 24, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

View Seminar >

DEPARTMENT SEMINAR

"The Challenge of Immature Respiratory Control Superimposed Upon an Immature Preterm Lung"


Donghan Lee, PhD
Donghan Lee, PhD
University of Louisville School of Medicine
Sept. 10, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Matthias Buck

View Seminar >

DEPARTMENT SEMINAR

"Functional dynamics via high-power relaxation dispersion: Molecular recognition, hierarchy of motions, and allostery"


Joseph A. Hill, MD, PhD
Joseph A. Hill, MD, PhD
University of Texas Southwestern Medical Center
Sept. 7, 2018 1:30 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

4TH ANNUAL MATTHEW N. LEVY LECTURE

"Heart Failure: Two Inflammatory Tales "


James D. Stockand, PhD
James D. Stockand, PhD
University of Texas Health Science Center - San Antonio
July 16, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SPECIAL SEMINAR

"Purinergic Regulation of Renal Na+ Excretion and Blood Pressure"


Xinghong Dai, PhD
Xinghong Dai, PhD
University of California – Los Angeles
May 1, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

View Seminar >

DEPARTMENT SPECIAL SEMINAR

"Mechanisms of viral capsid assembly and genome packaging "


Michael K. Rosen, PhD
Michael K. Rosen, PhD
University of Texas Southwestern Medical Center
April 30, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Michael Babinchak, PhD

View Seminar >

DEPARTMENT SEMINAR

"POSTPONED UNTIL 12/17/2018: Physical Mechanisms of Cell Organization on Micron Length Scales"


Peter J. Hunter, MNZM, DPhil, ME, FIPENZ (Hon.), FRSNZ, FRS
Peter J. Hunter, MNZM, DPhil, ME, FIPENZ (Hon.), FRSNZ, FRS
University of Auckland (NZ)
April 19, 2018 4 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

TECHNICAL TALK

"A mathematical physics and computer science framework for reproducible multiscale modelling in physiology"


Peter J. Hunter, MNZM, DPhil, ME, FIPENZ (Hon.), FRSNZ, FRS
Peter J. Hunter, MNZM, DPhil, ME, FIPENZ (Hon.), FRSNZ, FRS
University of Auckland (NZ)
April 18, 2018 4 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

FRONTIERS IN BIOLOGICAL SCIENCES LECTURE POSTPONED

"Cardiac research at the Auckland Bioengineering Institute "


Hiro Furukawa, PhD
Hiro Furukawa, PhD
Cold Spring Harbor Laboratory
April 17, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

View Seminar >

DEPARTMENT SPECIAL SEMINAR

"Structure and Biology of NMDA receptors "


Ralf Langen, PhD
Ralf Langen, PhD
University of Southern California - Keck School of Medicine - Zilkha Neurogenetic Institute
April 16, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Witold K. Surewicz, PhD

View Seminar >

DEPARTMENT SEMINAR

"Huntingtin Misfolding and Membrane Interaction – Implications for Huntington’s Disease"


Carol J. Deutsch, PhD
Carol J. Deutsch, PhD
University of Pennsylvania - Perelman School of Medicine
April 9, 2018 4 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"Ribosome-Peptide Pas de Deux: Tunnel Vision"


Wonpil Im, PhD
Wonpil Im, PhD
Lehigh University
April 2, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Matthias Buck

View Seminar >

DEPARTMENT SEMINAR

"Bacterial Outer Membranes and Interactions with Membrane Proteins"


Mark A. Knepper, MD, PhD
Mark A. Knepper, MD, PhD
National Heart, Lung, and Blood Institute (NIH)
March 19, 2018 4 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

6TH ANNUAL ULRICH HOPFER LECTURE

"Regulation of Aqp2 gene expression by vasopressin "


R. Tyler Miller, MD
R. Tyler Miller, MD
University of Texas Southwestern Medical Center
March 12, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SEMINAR

"Biophysical Contributions to Glomerular Disease Initiation and Progression"


Jean-Paul Armache, PhD
Jean-Paul Armache, PhD
University of California - San Francisco, School of Medicine
March 8, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

View Seminar >

DEPARTMENT SPECIAL SEMINAR

"Structural studies of macromolecules using electron cryo-microscopy (cryo-EM)"


Tian-Min Fu, PhD
Tian-Min Fu, PhD
Boston Children's Hospital / Harvard Medical School
March 5, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

View Seminar >

DEPARTMENT SPECIAL SEMINAR

"To Be or Not To Be: The Triggering of Cell Death Signaling by Protein Oligomerization"


Nami Tajima, PhD
Nami Tajima, PhD
Cold Spring Harbor Laboratory
Feb. 26, 2018 4 p.m. - 5 p.m.
School of Medicine E504
Hosted by:

View Seminar >

DEPARTMENT SEMINAR

"Molecular mechanisms of NMDA receptor function and regulation"


Mark S. P. Sansom, DPhil
Mark S. P. Sansom, DPhil
University of Oxford
Feb. 23, 2018 noon
School of Medicine E501
Hosted by: Matthias Buck

View Seminar >

DEPARTMENT & CCMSB JOINT SPECIAL SEMINAR

"Lipid-Protein Interactions Through a 'Computational Microscope': Molecular Simulation Studies of Complex Biological Membranes"


Wei Mi, PhD
Wei Mi, PhD
Harvard Medical School
Feb. 15, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

View Seminar >

DEPARTMENT SPECIAL SEMINAR

"Trap and Flip": Conformational Snapshots and Mechanism of a Lipid Flippase"


Jian Payandeh, PhD
Jian Payandeh, PhD
Genentech, Inc.
Feb. 12, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Soumili Chatterjee, PhD

View Seminar >

DEPARTMENT SEMINAR

"Structural basis for selective antagonism of Nav channels and ABC transporters"


Nazih L. Nakhoul, PhD
Nazih L. Nakhoul, PhD
Tulane University School of Medicine
Jan. 29, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SEMINAR

"Properties and regulation of renal ammonia transport by Rh glycoproteins"


Murali Prakriya, PhD
Murali Prakriya, PhD
Feinberg School of Medicine, Northwestern Universtiy
Jan. 22, 2018 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"The Molecular Physiology of store-operated CRAC channels"


Mark Parker, PhD
Mark Parker, PhD
State University of New York at Buffalo Jacobs School of Medicine and Biomedical Sciences
Nov. 20, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SEMINAR

"Slc4a11: a H+ channel in HCO3- transporter’s clothing"


Steven K. Backues, PhD
Steven K. Backues, PhD
Eastern Michigan University
Nov. 13, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Rajesh Ramachandran, PhD

View Seminar >

DEPARTMENT SEMINAR

"Bulk vs Selective: The Mechanisms of Cellular Self-Eating"


Ashutosh Agrawal, PhD
Ashutosh Agrawal, PhD
University of Houston
Nov. 6, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Rajesh Ramachandran, PhD

View Seminar >

DEPARTMENT SEMINAR

"Life at the interface is occasionally unstable"


Chris Ward, PhD
Chris Ward, PhD
University of Maryland School of Medicine/School of Nursing - Baltimore
Oct. 30, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Jessica M. Berthiaume, PhD

View Seminar >

DEPARTMENT SEMINAR

"Microtubules as Disease Modifiers and Therapeutic Targets in Striated Muscle"


Stephen J. Moss, PhD
Stephen J. Moss, PhD
Sackler School of Graduate Biomedical Sciences, Tufts University
Oct. 16, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"Mechanisms that regulate the efficacy of GABAergic inhibition and the pathophysiology of epilepsy"


Michaela Jansen, PharmD, PhD
Michaela Jansen, PharmD, PhD
Texas Tech University Health Sciences Center School of Medicine
Oct. 9, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"Towards a high-resolution structure of the proton-coupled folate transporter"


Emad Tajkhorshid, PhD
Emad Tajkhorshid, PhD
University of Illinois at Urbana-Champaign
Oct. 2, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Rossana Occhipinti, PhD

View Seminar >

DEPARTMENT SEMINAR

"Microscopic View of Mechanisms and Pathways for Material Transport Across the Cellular Membrane"


Jeanne M. Nerbonne, PhD
Jeanne M. Nerbonne, PhD
Washington University School of Medicine in St. Louis
Sept. 28, 2017 3 p.m. - 4 p.m.
School of Medicine E501
Hosted by:

View Seminar >

3RD ANNUAL MATTHEW N. LEVY LECTURE

"Diversity of Cardiac Ion Channel Regulatory Mechanisms "


Monte S. Willis, MD, PhD, MBA, FCAP, FAHA
Monte S. Willis, MD, PhD, MBA, FCAP, FAHA
University of North Carolina - Chapel Hill
Sept. 18, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Julian E. Stelzer, PhD

View Seminar >

DEPARTMENT SEMINAR

"Muscle-Specific Regulation of Autophagy and Its Potential Role in Protecting Against Sepsis-Induced Cardiomyopathy"


Damir Janigro, PhD
Damir Janigro, PhD
Flocel, Inc. / Cleveland Clnic Foundation / Lerner Research Institute
Sept. 11, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Joseph C. LaManna, PhD

View Seminar >

DCAPT SEMINAR

"Blood-brain barrier and neurological diseases "


Mark S. Shapiro, PhD
Mark S. Shapiro, PhD
University of Texas Health Science Center - San Antonio
May 1, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"M-type (KCNQ) potassium ion channels: Novel insights into structure, signaling and functional role in brain dysfunction"


David Eisner, DPhil, FRCP (Hon.), FMedSci
David Eisner, DPhil, FRCP (Hon.), FMedSci
University of Manchester (U.K.)
April 26, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SPECIAL SEMINAR

"Calcium in the heart: in and out of control "


Susan Wray, PhD, FRCOG, FMedSci
Susan Wray, PhD, FRCOG, FMedSci
University of Liverpool (U.K.)
April 25, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SPECIAL SEMINAR

"Hypoxia and uterine function – something old and something new "


Adam W. Smith, PhD
Adam W. Smith, PhD
University of Akron (OH)
April 24, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Matthias Buck

View Seminar >

DEPARTMENT SEMINAR

"Resolving molecular interfaces in biological membranes"


Jonathan A. Javitch, MD, PhD
Jonathan A. Javitch, MD, PhD
Columbia University College of Physicians and Surgeons / Columbia University Medical Center / New York State Psychiatric Institute
April 17, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Christopher P. Ford, PhD

View Seminar >

DEPARTMENT SEMINAR

"A tale of two substrates: a novel mechanism for neurotransmitter: sodium symport"


Christopher J. Lingle, PhD
Christopher J. Lingle, PhD
Washington University in St. Louis School of Medicine
April 10, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"Auxiliary subunits of BK channels: not so auxiliary"


Amira Klip, PhD
Amira Klip, PhD
Hospital for Sick Children (Toronto) / University of Toronto
March 22, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

View Seminar >

5TH ANNUAL ULRICH HOPFER LECTURE

"Insulin and exercise signals mobilizing glucose transporters in muscle cells "


Anthony G. Hudetz, DBM, PhD
Anthony G. Hudetz, DBM, PhD
University of Michigan Medical School
March 20, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Joseph C. LaManna, PhD

View Seminar >

DEPARTMENT SEMINAR

"Brain Dynamics and Consciousness: Insights from anesthetic modulation of neuronal circuits"


Il-man Kim, PhD
Il-man Kim, PhD
Medical College of Georgia / University of Augusta (GA)
March 16, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

View Seminar >

DEPARTMENT SEMINAR

"Beta-arrestin-mediated adrenergic receptor signaling and non-coding RNAs in heart failure"


Xuelin Lou, PhD
Xuelin Lou, PhD
University of Wisconsin - Madison
March 13, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Corey Smith, PhD

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DEPARTMENT SEMINAR

"Dynamin-mediated endocytosis in pancreatic beta cells: Mechanism, function and implication in diabetes"


Daniel Beard, PhD
Daniel Beard, PhD
University of Michigan Medical School
March 6, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Rossana Occhipinti, PhD

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DEPARTMENT SEMINAR

"Myocardial mechanical-energetic coupling in heart disease"


Aryn Gittis, PhD
Aryn Gittis, PhD
Carnegie Mellon University
Feb. 27, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Christopher P. Ford, PhD

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DEPARTMENT SEMINAR

"Cell-specific pallidal intervention induces long-lasting motor recovery in dopamine depleted mice"


Na Li, PhD
Na Li, PhD
Baylor College of Medicine
Feb. 21, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

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DEPARTMENT SEMINAR

"Epigenetic Regulation and Inflammasome: Novel Molecular Mechanisms in Atrial Fibrillation"


Pierre-Jean Corringer, PhD
Pierre-Jean Corringer, PhD
Pasteur Institute / French National Center for Scientific Research (CNRS)
Feb. 20, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sandip Basak, PhD

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DEPARTMENT SEMINAR

"Allosteric functioning of a bacterial pentameric channel-receptor"


Linda M. Hendershot, PhD
Linda M. Hendershot, PhD
St. Jude Children's Research Hospital / University of Tennessee Health Science Center
Feb. 13, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

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DEPARTMENT SEMINAR

"Dissecting the Sequence-Based Quality Control Code of the Resident ER Hsp70 System"


William J. Pearce, PhD
William J. Pearce, PhD
Loma Linda University School of Medicine
Feb. 6, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Joseph C. LaManna, PhD

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DEPARTMENT SEMINAR

"Fetal Programming in the Vasculature: Glucocorticoids, miRNA and Smooth Muscle Phenotype"


Sharlene Day, MD
Sharlene Day, MD
University of Michigan Medical School
Jan. 30, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Julian E. Stelzer, PhD

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DEPARTMENT SEMINAR

"Clinical and experimental insights into myosin binding protein C mutations for hypertrophic cardiomyopathy"


Zayd M. Khaliq, PhD
Zayd M. Khaliq, PhD
National Institute of Neurological Disorders and Stroke (NINDS / NIH)
Jan. 23, 2017 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Christopher P. Ford, PhD

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DEPARTMENT SEMINAR

"Dopaminergic neurons of the substantia nigra – integration and subpopulations"


Matthew S. Gentry, PhD
Matthew S. Gentry, PhD
University of Kentucky College of Medicine
Dec. 15, 2016 4 p.m.
School of Medicine E501
Hosted by:

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DEPARTMENT SPECIAL SEMINAR

"Lafora disease - defining the molecular basis for a metabolic epilepsy"


Junji Iwahara, PhD
Junji Iwahara, PhD
University of Texas Medical Branch - Galveston
Dec. 5, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

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DEPARTMENT SEMINAR

"How do proteins scan DNA?"


Fang Li, PhD
Fang Li, PhD
University of Minnesota - Twin Cities
Nov. 29, 2016 4 p.m.
School of Medicine E501
Hosted by:

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DEPARTMENT SEMINAR

"Coronavirus Spike Proteins: Structure, Function, and Vaccine Design "


E. James Petersson, PhD
E. James Petersson, PhD
University of Pennsylvania
Nov. 28, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"Studying the role of alpha-synuclein in Parkinson’s Disease using synthetic proteins"


Nicholas  G. Brown, PhD
Nicholas G. Brown, PhD
St. Jude Children's Research Hosptial
Nov. 21, 2016 4 p.m.
School of Medicine E501
Hosted by:

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DEPARTMENT SEMINAR

"Structural Mechanisms of Cell Cycle Regulation by the Anaphase-Promoting Complex/Cyclosome"


Sameer Varma, MD
Sameer Varma, MD
University of South Florida
Nov. 14, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

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DEPARTMENT SEMINAR

"Design principles for selective ion transport across membranes"


David M. Jameson, PhD
David M. Jameson, PhD
University of Hawai'i at Manoa
Oct. 31, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Rajesh Ramachandran, PhD

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DEPARTMENT SEMINAR

"Through a Glass, Darkly - Looking at Protein Interactions in and out of Cells"


Sam Senyo, PhD
Sam Senyo, PhD
Case Western Reserve University
Oct. 24, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Jessica M. Berthiaume, PhD

View Seminar >

DEPARTMENT SEMINAR

"Engineering tools to study and repair the broken heart"


Eric Gouaux, PhD
Eric Gouaux, PhD
Vollum Institute, Oregon Health and Science University
Oct. 19, 2016 4 p.m.
School of Medicine E501
Hosted by:

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FRONTIERS IN BIOLOGICAL SCIENCES LECTURE POSTPONED

"Music of the brain illuminated by molecular studies of the instruments: X-rays and electrons reveal architecture and mechanism of neurotransmitter receptors and transporters"


Themis Lazaridis, PhD
Themis Lazaridis, PhD
Graduate Center - City College of New York
Oct. 10, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Matthias Buck

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DEPARTMENT SEMINAR

"Peptide-stabilized membrane pores: insights from simulations"


Jonathan A. Epstein, MD
Jonathan A. Epstein, MD
Perelman School of Medicine, University of Pennsylvania
Oct. 7, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

2ND ANNUAL MATTHEW N. LEVY LECTURE

"Regulation of nuclear architecture drives cell fate"


Stephen G. Sligar, PhD
Stephen G. Sligar, PhD
University of Illinois at Urbana-Champaign
Oct. 3, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Amrita Samanta, PhD

View Seminar >

DEPARTMENT SEMINAR

"Revealing the Structure and Function of Membrane Proteins Through Nanotechnology"


Reid Gilmore, PhD
Reid Gilmore, PhD
University of Massachustts Medical School
Sept. 19, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"Oligosaccharyltransferase assembly lines to achieve efficient asparagine-linked glycosylation"


Walter F. Boron, MD, PhD
Walter F. Boron, MD, PhD
Case Western Reserve University
Sept. 12, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Jessica M. Berthiaume, PhD

View Seminar >

DEPARTMENT SEMINAR

"Overturning Overton: channel-mediated gas transport across cell membranes"


Zhiyong Lin, PhD
Zhiyong Lin, PhD
Case Western Reserve University
May 9, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

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DCAPT SEMINAR

"An emerging role for matricellular protein CCN3 in vascular biology"


Henry N. Higgs, PhD
Henry N. Higgs, PhD
Dartmouth College Geisel School of Medicine
May 2, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Rajesh Ramachandran, PhD

View Seminar >

DEPARTMENT SEMINAR

"Biochemical and cellular studies of mammalian mitochondrial fission"


Dimitar Nikolov, PhD
Dimitar Nikolov, PhD
Memorial Sloan Kettering Cancer Center
April 25, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Matthias Buck

View Seminar >

DEPARTMENT SEMINAR

"Structural Studies of Axon Guidance Molecules"


John A. Dani, PhD
John A. Dani, PhD
University of Pennsylvania - Perelman School of Medicine
April 18, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Christopher P. Ford, PhD

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DEPARTMENT SEMINAR

"Nicotinic and Dopaminergic Mechanisms of Plasticity and Addiction"


Craig Vander Kooi, PhD
Craig Vander Kooi, PhD
University of Kentucky College of Medicine
April 11, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Matthias Buck

View Seminar >

DEPARTMENT SEMINAR

"Role of Neuropilin in Endothelial Cell Function"


Ulrich Pohl, Prof. Dr.med.
Ulrich Pohl, Prof. Dr.med.
Ludwig Maximilians University
April 8, 2016 1 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

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DEPARTMENT SPECIAL SEMINAR

"Vascular connexins, all-rounders which mind more than just a gap (junction) "


Jie Zheng, PhD
Jie Zheng, PhD
University of California - Davis School of Medicine
April 4, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

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DEPARTMENT SEMINAR

"Activation of nociceptive TRPV1 channel by vanilloids"


Hassane Mchaourab, PhD
Hassane Mchaourab, PhD
Vanderbilt University School of Medicine
March 28, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"Principles of energy transduction and alternating access by secondary transporters"


Justin Taraska, PhD
Justin Taraska, PhD
National Heart, Lung, and Blood Institute (NIH)
March 21, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Rajesh Ramachandran, PhD

View Seminar >

DEPARTMENT SEMINAR

"Imaging the nanometer-scale structure of exocytosis and endocytosis"


Ernest M. Wright, PhD, DSci, FRS
Ernest M. Wright, PhD, DSci, FRS
University of California -Los Angeles School of Medicine
March 17, 2016 4 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

4TH ANNUAL ULRICH HOPFER LECTURE

"Basic Physiology to Translational Medicine: Lessons from SGLTS "


Kevin Bender, PhD
Kevin Bender, PhD
University of California - San Francisco (UCSF)
March 14, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Christopher P. Ford, PhD

View Seminar >

DEPARTMENT SEMINAR

"D3 dopamine receptor function defines a unique prefrontal pyramidal cell class"


Rossana Occhipinti, PhD
Rossana Occhipinti, PhD
Case Western Reserve University
March 9, 2016 2 p.m.
School of Medicine E501
Hosted by:

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INSTRUCTOR CANDIDATE SEMINAR

"Mathematical modeling of acid-base physiology "


Mohamed Trebak, PhD
Mohamed Trebak, PhD
Penn State Hershey College of Medicine
March 7, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: George R. Dubyak, PhD

View Seminar >

DEPARTMENT SEMINAR

"Multifaceted ORAI Channels: Novel Regulators of Vascular Function"


Cole M. Haynes, PhD
Cole M. Haynes, PhD
Gerstner Sloan Kettering Graduate School of Biomedical Sciences
Feb. 29, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Xin Qi, PhD

View Seminar >

DEPARTMENT SEMINAR

"Adaptive responses to mitochondrial dysfunction via a mito-UPR"


David G. Nicholls, PhD
David G. Nicholls, PhD
Buck Institute for Research on Aging
Feb. 22, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Xin Qi, PhD

View Seminar >

DEPARTMENT SEMINAR

"Investigating mitochondrial bioenergetics in the intact cell"


Wenzhen Duan, MD, PhD
Wenzhen Duan, MD, PhD
Johns Hopkins University School of Medicine
Feb. 15, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Xin Qi, PhD

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DEPARTMENT SEMINAR

"Translational Neurobiology: From Target Validation to Drug Development"


Yihong Ye, PhD
Yihong Ye, PhD
National Institute of Diabetes and Digestive and Kidney Diseases (NIH)
Feb. 8, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"Protein quality control and cancer therapy"


Anne K. Kenworthy, PhD
Anne K. Kenworthy, PhD
Vanderbilt University School of Medicine
Jan. 11, 2016 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Rajesh Ramachandran, PhD

View Seminar >

DEPARTMENT SEMINAR

"Assembly, dynamics, and function of membrane domains"


Jason Gestwicki, PhD
Jason Gestwicki, PhD
University of California, San Francisco
Dec. 7, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"Targeting Protein-Protein Interactions in the Molecular Chaperone Networks to Treat Protein Misfolding Diseases"


Patrick van der Wel, PhD
Patrick van der Wel, PhD
University of Pittsburgh
Nov. 30, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Rajesh Ramachandran, PhD

View Seminar >

DEPARTMENT SEMINAR

"Membrane-mediated activation of the proaptotic peroxidase function of mitochondrial cytochrome c"


Shu-ou Shan, PhD
Shu-ou Shan, PhD
California Institute of Technology
Nov. 23, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Rajesh Ramachandran, PhD

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DEPARTMENT SEMINAR

"ATPase and GTPase tangos during intracellular protein targeting"


Kenton J. Swartz, PhD
Kenton J. Swartz, PhD
National Institute of Neurological Disorders and Stroke (NINDS / NIH)
Nov. 16, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

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DEPARTMENT SEMINAR

"Structure and gating mechanism of temperature-sensing TRPV1 channels"


Alemayehu Gorfe, PhD
Alemayehu Gorfe, PhD
University of Texas Medical School - Houston
Nov. 9, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Matthias Buck

View Seminar >

DEPARTMENT SEMINAR

"Conformational plasticity and druggability of membrane-bound oncogenic K-Ras"


Louis-Eric Trudeau, PhD
Louis-Eric Trudeau, PhD
University of Montreal
Nov. 2, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Christopher P. Ford, PhD

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DEPARTMENT SEMINAR

"Axonal arborization and energetic metabolism of nigral dopamine neurons : a window into selective vulnerability in Parkinson's disease"


John E. Baenziger, PhD
John E. Baenziger, PhD
University of Ottawa
Oct. 26, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"Modulation of nicotinic receptor activity in both normal and diseased states"


Daniel N. Hebert, PhD
Daniel N. Hebert, PhD
University of Massachusetts - Amherst
Oct. 19, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

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DEPARTMENT SEMINAR

"N-glycan directed folding and quality control in the ER"


Peter Libby, MD
Peter Libby, MD
Brigham and Women's Hospital / Harvard Medical School
Oct. 12, 2015 3 p.m. - 4 p.m.
School of Medicine E501
Hosted by: Mukesh K. Jain, MD

View Seminar >

1ST ANNUAL MATTHEW N. LEVY LECTURE

"Inflammation in Atherosclerosis –a Translational Journey "


Michelle A. Puchowicz, PhD
Michelle A. Puchowicz, PhD
Case Western Reserve University
Sept. 28, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

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DCAPT SEMINAR

"Neuroprotective Properties of Ketosis"


Pei Tang, PhD
Pei Tang, PhD
University of Pittsburgh
Sept. 14, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

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DEPARTMENT SEMINAR

"Structural Insights Into Channel Gating and Drug Modulation"


Anita Aperia, MD, PhD
Anita Aperia, MD, PhD
Karolinska Institutet
May 21, 2015 4 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

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DEPARTMENT SPECIAL SEMINAR

"Identification of Na,K-ATPase as a signal transducer that regulates mitochondrial function "


Carol Toris, PhD
Carol Toris, PhD
Case Western Reserve University / University Hospitals of Cleveland
May 18, 2015 4 p.m.
School of Medicine E501
Hosted by:

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DCAPT SEMINAR

"Ocular Aqueous Humor Dynamics in Health and Disease"


Bradley K. Yoder, PhD
Bradley K. Yoder, PhD
University of Alabama School of Medicine
May 11, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Jeffrey L. Garvin, PhD

View Seminar >

DEPARTMENT SEMINAR

"Cilia, in vivo functions and connections to disease"


Sakthivel Sadayappan, PhD, MBA, FAHA, FAPS
Sakthivel Sadayappan, PhD, MBA, FAHA, FAPS
Loyola University - Chicago
April 27, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Julian E. Stelzer, PhD

View Seminar >

DEPARTMENT SEMINAR

"Unraveling disease mechanisms in cardiomyopathy with MYBPC3 gene mutations"


Richard J. Johnson, MD
Richard J. Johnson, MD
University of Colorado - Anschutz Medical Campus
April 22, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

3RD ANNUAL ULRICH HOPFER LECTURE

"Fructose and its Role in Obesity and Metabolic Syndrome "


Philip J. Thomas, PhD
Philip J. Thomas, PhD
University of Texas Southwestern Medical Center
April 20, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"Catching Mistakes Early: Quality Assurance before Quality Control"


Michael R. Bruchas, PhD
Michael R. Bruchas, PhD
Washington University-St. Louis School of Medicine
April 13, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Nicholas Courtney, PhD

View Seminar >

DEPARTMENT SEMINAR

"Dissection of GPCR Signaling and Neural Circuits in Stress"


Henry A. Lester, PhD
Henry A. Lester, PhD
California Institute of Technology
April 6, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Fraser J. Moss, PhD

View Seminar >

DEPARTMENT SEMINAR

"Inside-out Neuropharmacology, from Nicotinic Receptors to Psychiatric Medication"


Ted M. Dawson, MD, PhD
Ted M. Dawson, MD, PhD
Johns Hopkins University School of Medicine
March 30, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Xin Qi, PhD

View Seminar >

DEPARTMENT SEMINAR

"Regulation of Life and Death Decisions by Novel Cell Signaling Molecules"


Andrew D. McCulloch, PhD
Andrew D. McCulloch, PhD
University of California - San Diego
March 23, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Julian E. Stelzer, PhD

View Seminar >

DEPARTMENT SEMINAR

"Multi-Scale Modeling of the Failing Heart: From Mouse to Human"


Jianmin Gao, PhD
Jianmin Gao, PhD
Boston College
March 16, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"Targeting Membrane Lipids with Synthetic Molecules"


Jyoti Watters, PhD
Jyoti Watters, PhD
University of Wisconsin - Madison - School of Veterinary Medicine
March 9, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: David Litvin, PhD

View Seminar >

DEPARTMENT SEMINAR

"CANCELED: Epigenetic regulation of microglial activities by intermittent hypoxia"


David A. Harris, MD, PhD
David A. Harris, MD, PhD
Boston University School of Medicine
March 2, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Thomas Williams, PhD

View Seminar >

DEPARTMENT SEMINAR

"Prion Protein Neurotoxic Pathways"


Sokol Todi, PhD
Sokol Todi, PhD
Wayne State University - School of Medicine
Feb. 23, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Christopher P. Ford, PhD

View Seminar >

DEPARTMENT SEMINAR

"Keeping the enemy at bay: Preventing neurotoxicity in polyglutamine-depedent spinocerebellar ataxias"


Wolfgang Peti, PhD
Wolfgang Peti, PhD
Brown University
Feb. 2, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Matthias Buck

View Seminar >

DEPARTMENT SEMINAR

"Understanding the specificity of phosphatases"


Baron Chanda, PhD
Baron Chanda, PhD
University of Wisconsin - Madison
Jan. 26, 2015 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Soumili Chatterjee, PhD

View Seminar >

DEPARTMENT SEMINAR

"Thermodynamic insights into voltage-dependent gating of ion channels"


J. Kevin Foskett, PhD
J. Kevin Foskett, PhD
Perelman School of Medicine, University of Pennsylvania
Dec. 15, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: George R. Dubyak, PhD

View Seminar >

DEPARTMENT SEMINAR

"CALHM ion channels: How taste cells lacking synapses mediate neurotransmission"


Daniel J. Leahy, PhD
Daniel J. Leahy, PhD
Johns Hopkins University School of Medicine
Dec. 8, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Matthias Buck

View Seminar >

DEPARTMENT SEMINAR

"Molecular Basis of EGFR/HER2 Signaling and ErbB-targeted Cancer Therapies"


Andrew P. Hinck, PhD
Andrew P. Hinck, PhD
University of Texas Health Science Center - San Antonio
Dec. 2, 2014 noon - 1 p.m.
School of Medicine E501
Hosted by: Matthias Buck

View Seminar >

DEPARTMENT SPECIAL SEMINAR

"Structural studies of TGF-beta superfamily signaling proteins: New insights into diversification of function and new strategies for treating diseases caused by aberrant superfamily signaling "


Monte S. Willis, MD, PhD, MBA, FCAP, FAHA
Monte S. Willis, MD, PhD, MBA, FCAP, FAHA
University of North Carolina - Chapel Hill
Dec. 1, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Jessica M. Berthiaume, PhD

View Seminar >

DEPARTMENT SEMINAR

"The role of Muscle Ring Finger (MuRF) proteins in the regulation of diabetic cardiomyopathy and metabolism in vivo"


Jaideep Bains, PhD
Jaideep Bains, PhD
University of Calgary
Nov. 24, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Christopher P. Ford, PhD

View Seminar >

DEPARTMENT SEMINAR

"Temporal window for metaplasticity following stress"


Peter J. Thomas, PhD
Peter J. Thomas, PhD
Case Western Reserve University
Nov. 17, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Jessica M. Berthiaume, PhD

View Seminar >

DEPARTMENT SEMINAR

"Measuring edge importance: a quantitative analysis of the stochastic shielding approximation for random processes on graphs"


Xiao-Jiang Li, MD, PhD
Xiao-Jiang Li, MD, PhD
Emory University School of Medicine
Nov. 10, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Xin Qi, PhD

View Seminar >

DEPARTMENT SEMINAR

"Transgenic animal models of neurodegenerative diseases"


Bin Zhang, PhD
Bin Zhang, PhD
Cleveland Clinic Foundation
Nov. 3, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"The role of the early secretory pathway in health and diseases"


Edwin R. Chapman, PhD
Edwin R. Chapman, PhD
University of Wisconsin - Madison
Oct. 27, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Corey Smith, PhD

View Seminar >

DEPARTMENT SEMINAR

"Fusion pore structure, and factors that control the kinetics of synaptic transmission"


Vasanthi Jayaraman, PhD
Vasanthi Jayaraman, PhD
University of Texas Health Science Center - Houston (UTHealth Medical School)
Oct. 20, 2014 3 p.m. - 4 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"Moving and grooving of glutamate receptors"


Anthony L. Auerbach, PhD
Anthony L. Auerbach, PhD
State University of New York at Buffalo
Oct. 13, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"Ligand Binding, Channel Gating and Energy Change in a Synaptic Receptor"


Arun Anantharam, PhD
Arun Anantharam, PhD
Wayne State University
Oct. 6, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Corey Smith, PhD

View Seminar >

DEPARTMENT SEMINAR

"The regulation of secretory granule fusion and fusion modes in the adrenal chromaffin cell"


François M. Abboud
François M. Abboud
University of Iowa
Oct. 1, 2014 10:30 a.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

LEVY SYMPOSIUM

"Autonomic neural regulation of immune system: Implications for hypertension"


Donald M. Bers
Donald M. Bers
University of California, Davis
Oct. 1, 2014 4 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

LEVY SYMPOSIUM

"Calcium regulation and signaling in cardiac myocytes in health and disease"


Michael R.S. Hill, PhD, MBA
Michael R.S. Hill, PhD, MBA
Medtronic
Oct. 1, 2014 9:15 a.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

LEVY SYMPOSIUM

"Fundamentals of autonomic modulation applied as a new therapy for heart failure in medical devices"


Mark E. Dunlap, MD
Mark E. Dunlap, MD
MetroHealth Medical Center / Case Western Reserve University School of Medicine
Oct. 1, 2014 8:45 a.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

LEVY SYMPOSIUM

"Matthew Levy: The Gentleman Researcher"


Julian E. Stelzer, PhD
Julian E. Stelzer, PhD
Case Western Reserve University
Oct. 1, 2014 11:30 a.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

LEVY SYMPOSIUM

"Integrative control of cardiac muscle contraction"


Elizabeth McNally
Elizabeth McNally
The University of Chicago
Oct. 1, 2014 1:30 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

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LEVY SYMPOSIUM

"The genetic landscape of cardiomyopathy"


Yoram Rudy
Yoram Rudy
Washington University-St. Louis School of Medicine
Oct. 1, 2014 2:30 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

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LEVY SYMPOSIUM

"Arrhythmogenic substrates and arrhythmia mechanism in the human heart –insights from noninvasive mapping in patients"


E. Yvonne Jones, DPhil, FMedSci
E. Yvonne Jones, DPhil, FMedSci
University of Oxford
Sept. 22, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Matthias Buck

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DEPARTMENT SEMINAR

"Surface assemblies in cell guidance signalling systems"


Hiromi Sesaki, PhD
Hiromi Sesaki, PhD
Johns Hopkins University School of Medicine
Sept. 15, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Rajesh Ramachandran, PhD

View Seminar >

DEPARTMENT SEMINAR

"Mitochondrial dynamics in the brain and heart"


Manolis Doxastakis, MSc, PhD
Manolis Doxastakis, MSc, PhD
Argonne National Laboratory
Sept. 8, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Liqun Zhang, PhD

View Seminar >

DEPARTMENT SEMINAR

"Protein association in lipid membranes"


Eric M Small, PhD
Eric M Small, PhD
University of Rochester Medical Center
May 12, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Saptarsi M. Haldar, MD

View Seminar >

DEPARTMENT SEMINAR

"Transcriptional Regulation of Cardiac Remodeling"


Benjamin M Gaston, MD
Benjamin M Gaston, MD
Rainbow Babies & Children's Hospital of University Hospitals / Case Western Reserve University School of Medicine
May 5, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

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DCAPT SEMINAR

"Respiratory physiology of S-nitrosothiol-based signaling molecules"


Christian Aalkjaer, MD
Christian Aalkjaer, MD
Aarhus University (Denmark)
May 1, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

2ND ANNUAL ULRICH HOPFER LECTURE

"Ca2+ activated Cl- channels in smooth muscle "


Christopher M Dobson, FRS
Christopher M Dobson, FRS
University of Cambridge
April 24, 2014 4 p.m. - 5 p.m.
Wolstein Research Building Amphitheatre - WRB-1413
Hosted by: Matthias Buck

View Seminar >

FRONTIERS IN BIOLOGICAL SCIENCES LECTURE POSTPONED

"The Amyloid Phenomenon and its Significance "


Ruisheng Liu, MD, PhD
Ruisheng Liu, MD, PhD
University of Mississippi Medical Center
April 22, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Jeffrey L. Garvin, PhD

View Seminar >

DEPARTMENT SPECIAL SEMINAR

"A novel renal mechanism for salt-sensitive hypertension "


Bernard (Bob) Gutin, PhD
Bernard (Bob) Gutin, PhD
Medical College of Georgia / Teachers College, Columbia University
April 21, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Thomas M. Nosek, PhD

View Seminar >

DEPARTMENT SEMINAR

"How can youths develop lean and healthy bodies? A new perspective"


Douglas A. Bayliss, PhD
Douglas A. Bayliss, PhD
University of Virginia School of Medicine
April 14, 2014 4 p.m.
School of Medicine E501
Hosted by: George R. Dubyak, PhD

View Seminar >

DEPARTMENT SEMINAR

"Regulation of cellular excitability by modulation of background channels: mechanisms and physiological roles"


Robert K. Nakamoto, PhD
Robert K. Nakamoto, PhD
University of Virginia School of Medicine
April 7, 2014 4 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"How Gram negative bacteria eat: permeation through the outer membrane"


Merritt Maduke, PhD
Merritt Maduke, PhD
Stanford University School of Medicine
March 31, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Vera Moiseenkova-Bell, PhD

View Seminar >

DEPARTMENT SEMINAR

"Structural Dynamics of CLC Transporters"


Michael Regnier, PhD
Michael Regnier, PhD
University of Washington
March 24, 2014 4 p.m.
School of Medicine E501
Hosted by: Julian E. Stelzer, PhD

View Seminar >

DEPARTMENT SEMINAR

"How Do You Mend a Broken Heart: Mechanistic and Translational Studies of Cardiac Muscle Contraction"


Jonathan H. Lin, MD, PhD
Jonathan H. Lin, MD, PhD
University of California - San Diego
March 17, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"Mechanisms of Endoplasmic Reticulum Stress-Induced Cell Death and Pathology"


Jason Mears, PhD
Jason Mears, PhD
Case Western Reserve University
March 10, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Rajesh Ramachandran, PhD

View Seminar >

DEPARTMENT SEMINAR

"Structural studies of Drp1 self-assembly provide insights into the mechanism of mitochondrial fission"


Saptarsi M. Haldar, MD
Saptarsi M. Haldar, MD
Case Western Reserve University
March 3, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

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DEPARTMENT SEMINAR

"Targeting Chromatin Dependent Signaling in Heart Failure"


Mark A. Lemmon, PhD
Mark A. Lemmon, PhD
Perelman School of Medicine, University of Pennsylvania
Feb. 24, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Matthias Buck

View Seminar >

DEPARTMENT SEMINAR

"Diversity of Signaling Mechanisms in the Receptor Tyrosine Kinase Family"


Daniel L. Minor, Jr., PhD
Daniel L. Minor, Jr., PhD
University of California - San Francisco (UCSF)
Feb. 3, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"Structural and chemical biology studies of ion channels"


P. Hemachandra Reddy, PhD
P. Hemachandra Reddy, PhD
Oregon Health & Science University
Jan. 27, 2014 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Xin Qi, PhD

View Seminar >

DEPARTMENT SEMINAR

"Mitochondrial Damage and Neurodegenerative Diseases"


Allen W. Cowley, Jr., PhD
Allen W. Cowley, Jr., PhD
Medical College of Wisconsin
Jan. 13, 2014 4 p.m.
School of Medicine E501
Hosted by: Jeffrey L. Garvin, PhD

View Seminar >

DEPARTMENT SEMINAR

"Role of O2- and H2O2 production in the regulation of medullary blood flow, NaCl excretion and blood pressure"


Tobias Baumgart, PhD
Tobias Baumgart, PhD
University of Pennsylvania
Nov. 25, 2013 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Rajesh Ramachandran, PhD

View Seminar >

DEPARTMENT SEMINAR

"Membrane interaction mechanisms and curvature sorting of BAR domain proteins"


Donald E. Kohan, MD, PhD
Donald E. Kohan, MD, PhD
University of Utah School of Medicine
Nov. 18, 2013 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Pablo Cabral, MD

View Seminar >

DEPARTMENT SEMINAR

"New insights into control of renal collecting duct fluid and electrolyte transport"


Derek Taylor, PhD
Derek Taylor, PhD
Case Western Reserve University
Nov. 11, 2013 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"Structural and Biophysical Analysis of Telomere Assembly and Chromosome End Protection"


William Skach, MD
William Skach, MD
Oregon Health & Science University
Nov. 4, 2013 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Tingwei Mu, PhD

View Seminar >

DEPARTMENT SEMINAR

"From GFP to CFTR: Cotranslational Protein Folding in Cystic Fibrosis"


Lisa M. Ellerby, PhD
Lisa M. Ellerby, PhD
Buck Institute for Research on Aging
Oct. 28, 2013 4 p.m.
School of Medicine E501
Hosted by: Xin Qi, PhD

View Seminar >

DEPARTMENT SEMINAR

"What Can Stem Cells Tell us About Huntington's Disease"


Anant Parekh, PhD
Anant Parekh, PhD
University of Oxford
Oct. 21, 2013 4 p.m.
School of Medicine E501
Hosted by: William P. Schilling, PhD

View Seminar >

DEPARTMENT SEMINAR

"Store-operated calcium channels; gating and function"


Erik J. Henriksen, PhD
Erik J. Henriksen, PhD
University of Arizona
Oct. 7, 2013 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: John P. Kirwan, PhD

View Seminar >

DEPARTMENT SEMINAR

"Role of the Renin-Angiotensin-System in the Etiology of Insulin Resistance in Skeletal Muscle"


Jenny E. Hinshaw, PhD
Jenny E. Hinshaw, PhD
National Institute of Diabetes and Digestive and Kidney Diseases (NIH)
Sept. 30, 2013 4 p.m.
School of Medicine E501
Hosted by: Rajesh Ramachandran, PhD

View Seminar >

DEPARTMENT SEMINAR

"A dynamin mutant defines a super-constricted pre-fission step"


John T Williams, PhD
John T Williams, PhD
Oregon Health & Science University
Sept. 23, 2013 4 p.m.
School of Medicine E501
Hosted by: Christopher P. Ford, PhD

View Seminar >

DEPARTMENT SEMINAR

"Can a kinetic approach be used to understand acute opioid receptor desensitization?"


Robert Hsiu-Ping  Chow, MD, PhD
Robert Hsiu-Ping Chow, MD, PhD
University of Southern California - Keck School of Medicine
Sept. 16, 2013 4 p.m.
School of Medicine E501
Hosted by: Corey Smith, PhD

View Seminar >

DEPARTMENT SEMINAR

"Stimulus-secretion coupling in neuroendocrine cells"


Frank Jacono, MD
Frank Jacono, MD
Case Western Reserve University / University Hospitals of Cleveland
Sept. 9, 2013 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by:

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DCAPT SEMINAR

"Ventilatory pattern variability following acute lung injury: Insights into central mechanisms and clinical implications"


Christian Aalkjaer, MD
Christian Aalkjaer, MD
Aarhus University (Denmark)
Aug. 4, 2013 None Hosted by: Christian Aalkjaer, MD

View Seminar >

DEPARTMENT SEMINAR

"rbc test sem"


Joseph C. Wu, PhD, MD
Joseph C. Wu, PhD, MD
Stanford University School of Medicine
May 13, 2013 4 p.m.
School of Medicine E501
Hosted by: Isabelle Deschenes, PhD

View Seminar >

DEPARTMENT SEMINAR

"iPSCs for Cardiac Disease Modeling and Drug Screening"


Bing-Cheng Wang
Bing-Cheng Wang
Case Western Reserve University
May 7, 2013 4 p.m.
School of Medicine E501
Hosted by:

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DCAPT SEMINAR

"EphA2 Paradox: Oncogene or Tumor Suppressor Gene?"


John E. Hall, PhD
John E. Hall, PhD
University of Mississippi Medical Center
May 6, 2013 4 p.m.
School of Medicine E501
Hosted by: Panjamaporn Sangwung, PhD

View Seminar >

DEPARTMENT SEMINAR

"Pathophysiology of Hypertension in Obesity/Metabolic Syndrome"


John J. Lemasters, MD, PhD
John J. Lemasters, MD, PhD
Medical University of South Carolina
April 29, 2013 4 p.m.
School of Medicine E501
Hosted by: Andrea Romani, MD, PhD

View Seminar >

DEPARTMENT SEMINAR

"Iron Translocation from Lysosomes to Mitochondria in Oxidative Stress-Induced Injury"


L. Gabriel Navar, PhD
L. Gabriel Navar, PhD
Tulane University School of Medicine
April 12, 2013 4 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

1ST ANNUAL ULRICH HOPFER LECTURE

"The Intratubular Renin-Angiotensin System in Hypertension "


Christopher Miller, PhD
Christopher Miller, PhD
Brandeis University
April 8, 2013 4 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"Your precious bodily fluids: Channels and transporters counteracting fluoride toxicity"


James J. Chou, PhD
James J. Chou, PhD
Harvard Medical School
April 1, 2013 4 p.m.
School of Medicine E501
Hosted by: Susmita Borthakur, DPhil

View Seminar >

DEPARTMENT SEMINAR

"Molecular basis of UCP2 driven proton transport"


James U. Bowie, PhD
James U. Bowie, PhD
University of California – Los Angeles
March 25, 2013 4 p.m.
School of Medicine E501
Hosted by: Matthias Buck

View Seminar >

DEPARTMENT SEMINAR

"How do membrane proteins fold?"


Gabriela K. Popescu, PhD
Gabriela K. Popescu, PhD
State University of New York at Buffalo
March 18, 2013 4 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

DEPARTMENT SEMINAR

"NMDA receptors: learning from singles"


Augustine Choi, MD
Augustine Choi, MD
Brigham and Women's Hospital / Harvard Medical School
March 11, 2013 4 p.m.
School of Medicine E501
Hosted by: George R. Dubyak, PhD

View Seminar >

DEPARTMENT SEMINAR

"Title to be announced (date changed from 2/25/13)"


Richard J. Youle, PhD
Richard J. Youle, PhD
National Institute of Neurological Disorders and Stroke (NIH)
March 4, 2013 4 p.m.
School of Medicine E501
Hosted by: Xin Qi, PhD

View Seminar >

DEPARTMENT SEMINAR

"The role of E3 ligase Parkin and the kinase PINK1 in mitophagy and Parkinson's disease"


Mariela Mendez, PhD
Mariela Mendez, PhD
Henry Ford Hospital
Feb. 27, 2013 4 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SEMINAR

"Molecular Regulation of Renin Release: Role of SNAREs"


Gordon Mitchell, PhD
Gordon Mitchell, PhD
University of Wisconsin - Madison - School of Veterinary Medicine
Feb. 11, 2013 3 p.m.
School of Medicine E501
Hosted by: Corey Smith, PhD

View Seminar >

DEPARTMENT SEMINAR

"Spinal motor plasticity following intermittent hypoxia: implications for spinal injury" (PLEASE NOTE SPECIAL TIME)"


José L. Barneo, PhD, MD
José L. Barneo, PhD, MD
University of Seville
Jan. 30, 2013 4 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SEMINAR

"The carotid body; an oxygen-sensitive neurogenic niche"


Jian-Ping "J-P" Jin, PhD
Jian-Ping "J-P" Jin, PhD
Wayne State University - School of Medicine
Jan. 28, 2013 4 p.m.
School of Medicine E501
Hosted by: Thomas M. Nosek, PhD

View Seminar >

DEPARTMENT SEMINAR

"Troponin Regulation and Cardiac Function"


Yibin Wang, PhD
Yibin Wang, PhD
University of California – Los Angeles
Dec. 3, 2012 4 p.m.
School of Medicine E501
Hosted by: Mukesh K. Jain, MD

View Seminar >

DEPARTMENT SEMINAR

"From Molecules to Systems Biology for Cardiac Development and Diseases"


William J. "Bill"  Evans, PhD
William J. "Bill" Evans, PhD
GlaxoSmithKline
Nov. 19, 2012 4 p.m.
School of Medicine E501
Hosted by: John P. Kirwan, PhD

View Seminar >

DEPARTMENT SEMINAR

"Skeletal Muscle as a Target for Drug Discovery: New Indications for Aging and Cachexia"


Eduardo A. Perozo, PhD
Eduardo A. Perozo, PhD
The University of Chicago
Nov. 14, 2012 4 p.m.
School of Medicine E501
Hosted by: Sudha Chakrapani, PhD

View Seminar >

FRONTIERS IN BIOLOGICAL SCIENCES LECTURE POSTPONED

"Structural Basis of Voltage-Dependent Gating"


Robert Edwards, MD
Robert Edwards, MD
University of California, San Francisco
Nov. 5, 2012 4 p.m.
School of Medicine E501
Hosted by: Christopher P. Ford, PhD

View Seminar >

DEPARTMENT SEMINAR

"The Origin of Synaptic Vesicle Pools"


Toshinori Hoshi, PhD
Toshinori Hoshi, PhD
University of Pennsylvania - Perelman School of Medicine
Oct. 29, 2012 4 p.m.
School of Medicine E501
Hosted by:

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DEPARTMENT SEMINAR

"Fish oil and calcium-dependent potassium channels"


Christopher N. Wyatt, PhD
Christopher N. Wyatt, PhD
Wright State University - Boonshoft School of Medicine
Oct. 22, 2012 4 p.m.
School of Medicine E501
Hosted by: Christopher G. Wilson

View Seminar >

DEPARTMENT SEMINAR

"The role for AMP-activated protein kinase in the acute hypoxic ventilatory response"


Michael Jennings, PhD
Michael Jennings, PhD
University of Arkansas for Medical Sciences
Oct. 15, 2012 4 p.m.
School of Medicine E501
Hosted by: Mark D. Parker, PhD

View Seminar >

DEPARTMENT SEMINAR

"Some Lessons about Transport from Sulfur Assimilation in Yeast"


Natalia A. Trayanova, PhD
Natalia A. Trayanova, PhD
Johns Hopkins University
Oct. 1, 2012 4 p.m.
School of Medicine E501
Hosted by:

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DEPARTMENT SEMINAR

"Modeling Cardiac Function and Dysfunctionlation Targets"


Eric Delpire, PhD
Eric Delpire, PhD
Vanderbilt University School of Medicine
Sept. 24, 2012 4 p.m.
School of Medicine E501
Hosted by: George R. Dubyak, PhD

View Seminar >

DEPARTMENT SEMINAR

"Ste20 and WNK kinases in the regulation of Na+-(K+)-Cl- transport"


Frederick J. Sigworth, PhD
Frederick J. Sigworth, PhD
Yale School of Medicine
Sept. 17, 2012 4 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SEMINAR

"Cryo-EM study of a membrane protein in a membrane: the BK potassium channel"


Sharon Campbell, PhD
Sharon Campbell, PhD
University of North Carolina - Chapel Hill School of Medicine
Sept. 10, 2012 4 p.m.
School of Medicine E501
Hosted by:

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DEPARTMENT SEMINAR

"Ubiquitin and Redox-mediated Posttranslational Modification of Ras Regulates Ras Activity"


R. Ryan Geyer, PhD
R. Ryan Geyer, PhD
Case Western Reserve University
Sept. 7, 2012 8:40 a.m.
School of Medicine E504
Hosted by:

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GAS CHANNELS WORKSHOP

"Role of membrane proteins in oxygen transport in red blood cells"


Xue Qin, PhD
Xue Qin, PhD
Case Western Reserve University
Sept. 7, 2012 9:05 a.m.
School of Medicine E504
Hosted by:

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GAS CHANNELS WORKSHOP

"Structure determinants for CO2 transport of human aquaporin 5"


Rossana Occhipinti, PhD
Rossana Occhipinti, PhD
Case Western Reserve University
Sept. 7, 2012 9:30 a.m.
School of Medicine E504
Hosted by:

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GAS CHANNELS WORKSHOP

"Mathematical modeling of gas movements in an oocyte"


Robert Stroud, PhD
Robert Stroud, PhD
University of California – San Francisco School of Medicine
Sept. 6, 2012 4 p.m.
School of Medicine E501
Hosted by:

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GAS CHANNELS WORKSHOP

"Gas Channels Workshop"


Walter F. Boron, MD, PhD
Walter F. Boron, MD, PhD
Case Western Reserve University
Sept. 6, 2012 8:20 a.m.
School of Medicine E501
Hosted by:

View Seminar >

GAS CHANNELS WORKSHOP

"Gas Channels"


Emad Tajkhorshid, PhD
Emad Tajkhorshid, PhD
University of Illinois at Urbana-Champaign
Sept. 6, 2012 9:10 a.m.
School of Medicine E501
Hosted by:

View Seminar >

GAS CHANNELS WORKSHOP

"Visualizing gas permeation pathways through proteins at sub-Angstrom Resolution"


David Weiner
David Weiner
University of Florida
Sept. 6, 2012 3:10 p.m.
School of Medicine E501
Hosted by:

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GAS CHANNELS WORKSHOP

"Role of Rh glycoproteins in gas transport–lessons from in vitro model systems"


Bhanu Jena
Bhanu Jena
Wayne State University
Sept. 6, 2012 1:05 p.m.
School of Medicine E501
Hosted by:

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GAS CHANNELS WORKSHOP

"Involvement of elevated membrane cholesterol on G-protein regulated water and gas transport in biological membranes"


Volker Endeward
Volker Endeward
University of Hannover
Sept. 6, 2012 11:15 a.m.
School of Medicine E501
Hosted by:

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GAS CHANNELS WORKSHOP

"Intrinsic CO2 permeability of cell membranes and effect of cholesterol and aquaporin"


Gerolf Gros
Gerolf Gros
University of Hannover
Sept. 6, 2012 10:25 a.m.
School of Medicine E501
Hosted by:

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GAS CHANNELS WORKSHOP

"Measuring cellular CO2 permeability by 18O exchange-methodology and results on red blood cells"


Jeffrey L. Garvin, PhD
Jeffrey L. Garvin, PhD
Case Western Reserve University
Sept. 6, 2012 1:55 p.m.
School of Medicine E501
Hosted by:

View Seminar >

GAS CHANNELS WORKSHOP

"NO transport by aquaporin 1"


Blair Geho, MD, PhD
Blair Geho, MD, PhD
Case Western Reserve University
May 7, 2012 4 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SEMINAR

"The role of insulin in regulating hepatic glucose storage in type 1 diabetes mellitus"


Shai Silberberg, PhD
Shai Silberberg, PhD
NINDS / NIH
April 30, 2012 4 p.m.
School of Medicine E501
Hosted by:

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DEPARTMENT SEMINAR

"Architecture of the Pore and Gating Motions in P2X Receptor Channels"


Holger Sondermann, PhD
Holger Sondermann, PhD
Cornell University College of Veterinary Medicine
April 2, 2012 4 p.m.
School of Medicine E501
Hosted by: Rajesh Ramachandran, PhD

View Seminar >

DEPARTMENT SEMINAR

"Molecular Mechanisms of Membrane Deformation"


Lukas K. Tamm, PhD
Lukas K. Tamm, PhD
University of Virginia
March 19, 2012 4 p.m.
School of Medicine E501
Hosted by: Matthias Buck

View Seminar >

DEPARTMENT SEMINAR

"Assembly of the synaptic exocytotic fusion machine"


Julie A Theriot, PhD
Julie A Theriot, PhD
Stanford University School of Medicine
March 5, 2012 4 p.m.
School of Medicine E501
Hosted by:

View Seminar >

DEPARTMENT SEMINAR

"Mechanics and Dynamics of Cell Motility"


Charles Kunos
Charles Kunos
University Hospitals
Feb. 20, 2012 4 p.m.
School of Medicine E501
Hosted by: Joseph C. LaManna, PhD

View Seminar >

DEPARTMENT SEMINAR

"Ribonucleotide redactase inhibitors in oncology"


Jeffrey Brodsky
Jeffrey Brodsky
University of Pittsburgh
Feb. 13, 2012 4 p.m.
School of Medicine E501
Hosted by: Joseph C. LaManna, PhD

View Seminar >

DEPARTMENT SEMINAR

"Molecular chaperones, protein quality control, and conformational diseases"


Jeffrey S. Abramson
Jeffrey S. Abramson
UCLA
Feb. 6, 2012 4 p.m.
School of Medicine E501
Hosted by:

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DEPARTMENT SEMINAR

"Crystal structures of vSGLT: reveal mechanism of Na+/Sugar cotransport"


Benjamin D. Humphreys
Benjamin D. Humphreys
Harvard Medical School
Jan. 30, 2012 4 p.m.
School of Medicine E501
Hosted by: Ulrich Hopfer, MD, PhD

View Seminar >

DEPARTMENT SEMINAR

"Cellular Mechanisms of Kidney Repair and Fibrosis: Implications for Regenerative Medicine"


Anne Hamik
Anne Hamik
Case Western Reserve University
Jan. 9, 2012 4 p.m.
School of Medicine E501
Hosted by:

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DEPARTMENT SEMINAR

"KLF4 and Angiogenesis"


David Chan
David Chan
California Institute of Technology
Dec. 19, 2011 4 p.m.
School of Medicine E501
Hosted by: Xin Qi, PhD

View Seminar >

DEPARTMENT SEMINAR

"Physiological functions of mitochondrial dynamics"


Bruce Bean
Bruce Bean
Harvard Medical School
Dec. 12, 2011 4 p.m. - 5 p.m.
School of Medicine E501
Hosted by: Christopher P. Ford, PhD

View Seminar >

DEPARTMENT SEMINAR

"Spontaneous electrical activity of mammalian central neurons"


Martin E. Young
Martin E. Young
University of Alabama
Nov. 28, 2011 4 p.m.
School of Medicine E501
Hosted by: Margaret P. Chandler, PhD

View Seminar >

DEPARTMENT SEMINAR

"Timing Is Everything – Emerging Roles for the Cardiomyocyte Circadian Clock"


Aurelio Galli
Aurelio Galli
Vanderbilt University
Nov. 21, 2011 4 p.m.
School of Medicine E501
Hosted by: Andrea Romani, MD, PhD

View Seminar >

DEPARTMENT SEMINAR

"How the Big GULP Cures the Fat Brain: Striatal Insulin Resistance and GLP-1 Signaling"


Henk Granzier
Henk Granzier
University of Arizona
Oct. 31, 2011 4 p.m.
School of Medicine E501
Hosted by: Julian E. Stelzer, PhD

View Seminar >

DEPARTMENT SEMINAR

"Role of titin in muscle function and disease"


R. John Solaro
R. John Solaro
University of Illinois at Chicago
Oct. 17, 2011 4 p.m.
School of Medicine E501
Hosted by: Julian E. Stelzer, PhD

View Seminar >

DEPARTMENT SEMINAR

"Signaling to and from Cardiac Sarcomeres"


Mitchell Chesler
Mitchell Chesler
New York University
Oct. 10, 2011 4 p.m.
School of Medicine E501
Hosted by:

View Seminar >

DEPARTMENT SEMINAR

"Regulation and Modulation of Extracellular pH & Its Impact on Excitatory Synaptic Transmission"


Michael F. Romero, PhD
Michael F. Romero, PhD
Mayo Clinic College of Medicine
Oct. 3, 2011 4 p.m.
School of Medicine E501
Hosted by:

View Seminar >

DEPARTMENT SEMINAR

"Stoned flies, cystic fibrosis and glaucoma: Roles of bicarbonate transporting membrane proteins"


Manfred Lindau
Manfred Lindau
Case Western Reserve University
Sept. 26, 2011 4 p.m.
School of Medicine E501
Hosted by: Corey Smith, PhD

View Seminar >

DEPARTMENT SEMINAR

"How SNAREs open the fusion pore"


Theresa Torres Pizarro
Theresa Torres Pizarro
Case Western Reserve University
Sept. 19, 2011 4 p.m.
School of Medicine E501
Hosted by:

View Seminar >

DEPARTMENT SEMINAR

"Epithelial-Immune Cell Interactions in the Pathogenesis of Experimental Crohn’s Disease"


Peter M. MacFarlane
Peter M. MacFarlane
Rainbow Babies and Children’s Hospital
Sept. 12, 2011 4 p.m.
School of Medicine E501
Hosted by: Walter F. Boron, MD, PhD

View Seminar >

DEPARTMENT SEMINAR

"Physiological responses to intermittent hypoxia"


Raif Musa Aziz
Raif Musa Aziz
University of Sao Paulo, Brazil
June 1, 2011 4 p.m.
School of Medicine E501
Hosted by:

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DCAPT SEMINAR

"CO2 and NH3 transport through Aquaporins and Rh proteins expressed in Xenopus oocytes"


Sichun Yang
Sichun Yang
Case Western Reserve University
May 16, 2011 4 p.m.
School of Medicine E501
Hosted by:

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DCAPT SEMINAR

"Integrative Approaches into Multidomain Protein Assemblies"


Nathan D. Price
Nathan D. Price
University of Illinois at Urbana-Champaign
May 9, 2011 4 p.m. - 4:45 p.m.
School of Medicine E501
Hosted by:

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DEPARTMENT SEMINAR

"Integrative Approaches to Genome-Scale Biological Networks"


Laura E. Nagy
Laura E. Nagy
Cleveland Clinic Foundation
April 25, 2011 4 p.m. - 4:45 p.m.
School of Medicine E501
Hosted by: Andrea Romani, MD, PhD

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DEPARTMENT SEMINAR

"Innate Immunity and Alcoholic Liver Disease"


M. Michael Wolfe
M. Michael Wolfe
Case Western Reserve University
Dec. 20, 2010 4 p.m.
School of Medicine E501
Hosted by:

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DCAPT SEMINAR

"Obesity, Incretins, and the GI Tract: You Are What You Eat"