CWRU Links
Sichen (Susan) Shao, PhD
Associate Professor of Cell Biology
Harvard Medical School
PhD, Cell, Molecular, Developmental Biology and Biophysics, National Institutes of Health and Johns Hopkins University - NIH partnerships program
BSE, Chemical Engineering, Princeton University

Mailing Address:

Research Interests

The Shao Lab studies cellular mechanisms that surveil different steps of protein biosynthesis to regulate gene expression and maintain protein homeostasis. How quality control factors distinguish rare aberrant products from similar biosynthetic intermediates is a fundamental problem in biomedical science. The Shao Lab biochemically reconstitutes quality control pathways that act on ribosomes during protein synthesis and that sort membrane proteins to different organelles. Combining these experimental systems with mechanistic and structural approaches generates molecular-level insights into physiological processes essential for cell survival, proliferation, and differentiation.


Related Links