The majority of faculty offices, laboratories, teaching facilities, and administrative offices are located on the 5th and 6th floors of the Robbins Building, located in the East Wing of the School of Medicine. These two floors are interconnected by a glass balcony that combines the 25,000 square feet of space, greatly facilitating exchange between them. The department was designed using an open configuration model with a minimal number of doors and partitions. It incorporates 30 modular laboratories, offices, and common facilities with highly efficient space utilization and a positive and pleasant working environment.
Within this space lives The Protein Expression Purification Crystallization and Biophysics Core (PEPCMBC), which contains high-throughput robotics to facilitate protein crystallization. The PEPCMBC is open to the public with minimum user fees. Additional research buildings, housing, offices, and laboratories for the faculty are located at the Lerner Research Institute at the Cleveland Clinic Foundation, the Rammelkamp Research Building at MetroHealth Medical Center, and the Louis Stokes VA Medical Center. The facilities on all four campuses include state-of-the-art instrumentation for studies in Biophysics, Cell Biology, Electrophysiology, Molecular Biology, Structural Biology, and Transport Metabolism. Instrumentation includes several high-field NMR spectrometers, EPR, digital subtraction fluorescence imaging, and atomic force microscopy. Investigators in the department also have access to many other facilities and research centers located on the Case Western Reserve Medical School campus including an: