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Matthew D. Shoulders, PhD
Whitehead Career Development Associate Professor
Massachusetts Institute of Technology
PhD, Organic Chemistry, University of Wisconson - Madison

Mailing Address:
Cambridge , MA

Research Interests

The Shoulders Lab is developing and applying a chemical biology and small molecule-derived toolbox to probe the cell's protein folding network and manipulate it in defined ways. We employ a multi-disciplinary approach to understand how the cell remodels itself to address challenges to protein homeostasis, to elucidate the pathophysiology of protein folding-related diseases with poorly defined etiologies, and to target the biological processes we uncover for the development of first-in-class small molecule drugs.


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