1. Zhang PP, Benske TM, Ahn LY, Schaffer AE, Paton JC, Paton AW, Mu TW, Wang YJ (2024) Adapting the endoplasmic reticulum proteostasis rescues epilepsy-associated NMDA receptor variants. Acta Pharmacologica Sinica, DOI: 10.1038/s41401-023-01172-w. PMID: 37803141.
2. Wang YJ, Di XJ, Zhang PP, Chen X, Williams MP, Han DY, Nashmi R, Henderson BJ, Moss FJ, Mu TW (2024) Hsp47 promotes biogenesis of multi-subunit neuroreceptors in the endoplasmic reticulum. Elife, DOI: 10.7554/eLife.84798. PMID: 38963323.
1. Wang YJ, Seibert H, Ahn LY, Schaffer AE, Mu TW (2024) Pharmacological chaperones restore proteostasis of epilepsy-associated GABAA receptor variants. Pharmacological Research, DOI: 10.1016/j.phrs.2024.107356. PMID: 37131660.
2. Wang YJ, Di XJ, Zhang PP, Chen X, Williams MP, Han DY, Nashmi R, Henderson BJ, Moss FJ, Mu TW (2024) Hsp47 promotes biogenesis of multi-subunit neuroreceptors in the endoplasmic reticulum. Elife, DOI: 10.7554/eLife.84798. PMID: 38963323.
"Human neural assembloids to study neuronal circuits development and disease"
Dr. Boron will be the recipient of the 2025 Christian Bohr Prize this coming September at the 40th Congress of the International Union of Physiological Sciences / Europhysiology 2025. IUPS2025
Identification of Novel Murine RPTPy and RPTPs Splice Variants and the Role of Rptps in Modulating the Neuronal and Astrocytic Intracellur pH Response to Metabolic or Respiratory Acidosis
The CWRU Postdoc Association has arranged for speakers via Zoom to share their journey as a postdoc, suggest specific professional development, discuss their current role, and offer advice for someone looking into that career path. Attendees will have the opportunity to ask questions at the end of each presentation. See the attached flyer for more detailed bio info on the speaker and to RSVP.
In the Master of Science in Aerospace Physiology program, our students receive advanced training in aerospace physiology to prepare for a career in this cutting edge field.
Reception will follow immediately afterward with food and beverages.
G protein regulation by regulators of G protein signaling (RGS) proteins play a key role in vascular tone maintenance. The loss of Gi/o and Gq/11 regulation by RGS2 and RGS5 in non-pregnant mice is implicated in augmented vascular tone and decreased uterine blood flow (UBF). RGS2 and 5 are closely related and co-expressed in uterine arteries (UA).
Human cells have many mechanisms to detect and respond to bacterial and viral intruders. Proteins that recognize bacterial cell wall components can coat the surface of invading bacteria and serve as a scaffold for the assembly of signaling proteins and antimicrobial enzymes.
Mitochondrial dysfunction has been implicated in various types of cardiovascular disease including hypertension. Mitochondrial fission fusion balance is critical to mitochondrial quality control, whereas enhanced fission has been reported in several models of cardiovascular disease.
Darshan Attmaram's research on cell heterogeneity in microdissected rat nephron segments received an "Honorable Mention" by the APS Physiological Omics Interest Group at the Physiology Summit 2024.