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Henk Granzier
University of Arizona

Mailing Address:
Medical Research Building (MRB), room 325
1656 E. Mabel
Tucson , AZ 85724-0000
Phone: 520-626-3641
Fax: 520-626-7600

Research Interests

Our research is focused on elucidating the structure and function of titin and nebulin, two large filamentous proteins found in muscle. We use a range of model systems with a major focus on KO and TG mouse models. The techniques that we use range from single molecule mechanics, (immuno) electron microscopy, exon microarray analysis, in vitro motility assays, low angle X-ray diffraction, cell physiology (including calcium imaging), muscle mechanics, and isolated heart physiology.