In innate immunity, the inflammasomes are large molecular machineries that are responsible for combating microbial infections. A canonical inflammasome complex contains the sensor protein, the adaptor protein called apoptosis-associated speck-like protein (ASC), and the cysteine protease [read more]
Biogenesis of membrane proteins is controlled by the protein homeostasis (proteostasis) network. Our lab has been focusing on protein quality control of ?-aminobutyric acid type A receptors (GABAARs), the major inhibitory neurotransmitter-gated ion channels in mammalian central nervous system [read more]
