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Anne E. Carlson, PhD
Associate Professor
University of Pittsburgh

Mailing Address:

Research Interests

The Carlson laboratory studies signaling events in excitable cells. Specifically, it is focused on:


•    Uncovering the signaling pathways evoked in the egg within minutes of sperm entry.  
•    Understand the molecular mechanisms of polyspermy block; preventing fertilization by more than one sperm.
•    Elucidate the role of lipid PIP2 in early embryonic development.

Regulation of the Ca2+ activated Cl- channel TMEM16a:

•    Uncover the role of PIP2 in regulating TMEM16a gating
•    Determine signaling pathways that open TMEM16a channels


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