The Carlson laboratory studies signaling events in excitable cells. Specifically, it is focused on:

Fertilization:

•    Uncovering the signaling pathways evoked in the egg within minutes of sperm entry.  
•    Understand the molecular mechanisms of polyspermy block; preventing fertilization by more than one sperm.
•    Elucidate the role of lipid PIP2 in early embryonic development.

Regulation of the Ca2+ activated Cl- channel TMEM16a:

•    Uncover the role of PIP2 in regulating TMEM16a gating
•    Determine signaling pathways that open TMEM16a channels

Source: https://www.carlsonscience.com/overview