Physiology & Biophysics

Seminars


During the academic year, we sponsor a seminar on most Mondays at 4:00 PM, in the Lecture Hall (E501). We pride ourselves on presenting, at almost every seminar, an eminent scholar from around the country or around the globe.



Upcoming Seminars


DEPARTMENT SEMINAR

"Towards a structural understanding of aquaporin function and activation: a hybrid Electron microscopic and X-ray crystallographic approach"

Ardeschir Vahedi-Faridi, PhD
Oct. 22, 2018 4 p.m. - 5 p.m.
School of Medicine E501


FRONTIERS IN BIOLOGICAL SCIENCES LECTURE

"Human GABAA Receptor Structures and Signaling Mechanisms"

Radu Aricescu, PhD
Hosted by:
Sudha Chakrapani, PhD
Oct. 24, 2018 4 p.m.
School of Medicine E501

Type-A γ-aminobutyric receptors (GABAARs) are the principal mediators of rapid inhibitory synaptic transmission in the human brain. They are pentameric ligand-gated chloride channels, with a very rich pharmacology, involved in virtually all brain functions. Some of the GABAAR modulators, including benzodiazepines and anaesthetics, are among the most successful drugs in clinical use, and often substances of abuse. Without structural data, the molecular basis for pharmacological modulation of GABAARs remained virtually unknown. I will discuss our path to high resolution structural characterisation of human heteromeric GABAARs and their complexes with multiple small molecule ligands. This work provides unprecedented insights into the mechanisms of GABA-ergic signalling, a reliable structural framework to integrate decades of physiology and pharmacology research and a rational basis for the development of novel GABAAR modulators.


DEPARTMENT SEMINAR

"The Role of Bioactive Lipids in Transient Receptor Potential Channels Function"

Julio Cordero-Morales, PhD
Hosted by:
Sudha Chakrapani, PhD
Oct. 29, 2018 4 p.m. - 5 p.m.
School of Medicine E501


DEPARTMENT SEMINAR

"Autonomic Modulation of Venous Capacitance in the Pathophysiology of Acute HF"

Mark E. Dunlap, MD
Nov. 5, 2018 4 p.m. - 5 p.m.
School of Medicine E501


DEPARTMENT SEMINAR

"Structural characterization of a nucleotide-powered endonuclease complex involved in bacterial defense"

Joshua S. Chappie, PhD
Hosted by:
Rajesh Ramachandran, PhD
Nov. 12, 2018 4 p.m. - 5 p.m.
School of Medicine E501


DEPARTMENT SEMINAR

"Organelle targeting of tail-anchored proteins"

Cory Dunn, PhD
Hosted by:
Rajesh Ramachandran, PhD
Nov. 19, 2018 4 p.m. - 5 p.m.
School of Medicine E501


DEPARTMENT SEMINAR

"Discover New Genes and Therapies for Cardiomyopathy via Zebrafish Genetics"

Xiaolei Xu, PhD
Hosted by:
Julian E. Stelzer, PhD
Jan. 14, 2019 4 p.m. - 5 p.m.
School of Medicine E501


DEPARTMENT SEMINAR

"Chemistry at the membrane: an unnatural approach in a natural setting"

Sharona Gordon, PhD
Hosted by:
Sudha Chakrapani, PhD
March 11, 2019 4 p.m. - 5 p.m.
School of Medicine E501


DEPARTMENT SEMINAR

"The retrotrapezoid nucleus: A site for chemoreceptors or just a relay for other pH sensors?"

George B. Richerson, MD, PhD
Hosted by:
Walter F. Boron, MD, PhD
March 25, 2019 4 p.m. - 5 p.m.
School of Medicine E501


DEPARTMENT SEMINAR

"Molecular Dynamics Simulations of Membrane Permeability"

Richard W. Pastor, PhD
Hosted by:
Matthias Buck, MA, DPhil
May 6, 2019 4 p.m. - 5 p.m.
School of Medicine E501



Past Seminars


SPECIAL DEPARTMENT SEMINAR

"Cryo-EM, an imaging tool beyond crystallography"

Wah Chiu, PhD
Hosted by:
Sudha Chakrapani, PhD
Oct. 17, 2018 1 p.m.
School of Medicine E501

DEPARTMENT SEMINAR

"Critical windows of respiratory system development - adverse consequences to early life insults"

Peter MacFarlane, PhD
Oct. 15, 2018 4 p.m. - 5 p.m.
School of Medicine E501

DEPARTMENT SEMINAR

"Magnetic Resonance Studies of Membrane Proteins"

Gary A. Lorigan, PhD
Hosted by:
Sudha Chakrapani, PhD
Oct. 8, 2018 4 p.m. - 5 p.m.
School of Medicine E501

DEPARTMENT SEMINAR

"New ideas in glaucoma therapeutics"

Carol Toris, PhD
Oct. 1, 2018 4 p.m. - 5 p.m.
School of Medicine E501

DEPARTMENT SEMINAR

"The Challenge of Immature Respiratory Control Superimposed Upon an Immature Preterm Lung"

Richard J. Martin, MD
Sept. 24, 2018 4 p.m. - 5 p.m.
School of Medicine E501

DEPARTMENT SEMINAR

"Functional dynamics via high-power relaxation dispersion: Molecular recognition, hierarchy of motions, and allostery"

Donghan Lee, PhD
Hosted by:
Matthias Buck, MA, DPhil
Sept. 10, 2018 4 p.m. - 5 p.m.
School of Medicine E501

4TH ANNUAL MATTHEW N. LEVY LECTURE

"Heart Failure: Two Inflammatory Tales"

Joseph A. Hill, MD, PhD
Hosted by:
Walter F. Boron, MD, PhD
Sept. 7, 2018 1:30 p.m.
School of Medicine E501

SPECIAL DEPARTMENT SEMINAR

"Purinergic Regulation of Renal Na+ Excretion and Blood Pressure"

James D. Stockand, PhD
Hosted by:
Walter F. Boron, MD, PhD
July 16, 2018 4 p.m. - 5 p.m.
School of Medicine E501

SPECIAL DEPARTMENT SEMINAR

"Mechanisms of viral capsid assembly and genome packaging"

Xinghong Dai, PhD
May 1, 2018 4 p.m. - 5 p.m.
School of Medicine E501

DEPARTMENT SEMINAR

"POSTPONED UNTIL 12/17/2018: Physical Mechanisms of Cell Organization on Micron Length Scales"

Michael K. Rosen, PhD
Hosted by:
Michael Babinchak
April 30, 2018 4 p.m. - 5 p.m.
School of Medicine E501



View Archived Seminars