Welcome to the Department of Physiology and Biophysics!
Welcome to the Department of Physiology and Biophysics! We are over 170 faculty, fellows, students, and staff. Building on strong traditions, we strive to be a world leader in our parallel missions of research, teaching, and service. Our founding chair John Macleod was a future Nobel Laureate, Corneille Heymans was another laureate trained in the Department, and a Lasker Award winner Carl J. Wiggers chaired the Department for a generation. Our research mission benefits from a rare combination of faculty who address important translational problems in physiology and biophysics across a broad spectrum of integration—from the level of the atomic structure of molecules, through living cells and organ systems, and up to the whole organism. The major programmatic foci of our research are cardiovascular, renal, and neuronal function in health and disease. Our educational mission includes a strong PhD-training program as well as a new Master’s program in medical physiology that has attracted considerable interest. Our service mission has a strong impact at the local, national, and international levels.
Mission: research, education, service
Research Interest: integration of physiology and biophysics from atom to whole organism
Former President of FASEB, Secretary General of the IUPS, Co-director of Case’s MSTP
Co-home to textbook Medical Physiology
Post-Bacc Application Deadline Approaching
June 5, 2013
Application deadline: July 1, 2013
July 1, 2013 is the official deadline for submitting applications for the MS in Medical Physiology Program (Post-Bacc Program). If you have not yet begun the application process, go to the University's online application system. You must click the online 'submit' button by July 1 to be officially submitted. Note that your application packet need not be fully complete at the time you click 'submit'. Once you click 'submit,' your materials automatically transfer from the Graduate School to the Department and we can work with you to complete the application (e.g., letters of reference, test scores). Contact us if you need assistance.
2013 Department Retreat
Oct. 3, 2013
Oct. 4, 2013
The Department will sponsor a Department Retreat on October 3rd and 4th at Sawmill Creek Resort in Huron/Sandusky, Ohio. Retreats consist of informal scientific presentations by principal investigators, students, and post-doctoral fellows.
Dissertation Seminar: Seong-Ki Lee
June 20, 2013
Molecular action of an electrogenic Na/HCO3 cotransporter (NBCe1)
Reception at 4:00 PM on 5th floor bridge
Department Welcomes Jeff Garvin
Nov. 28, 2012
The Department welcomes Jeff Garvin, who joined us November 28, 2012. He brought with him four members of his laboratory from Henry Ford Hospital in Detroit where he was Division Head of Hypertension and Vascular Research in the Department of Internal Medicine. Jeff is an authority on epithelia transport and the role of the kidneys in the regulation of blood pressure and the genesis of hypertension. In 2011, Jeff was the recipient of the prestigious Gottschalk Award of the American Physiological Society-one of the most prestigious honors in the renal field. He has authored more than 135 publications in peer-reviewed journals and has served on numerous NIH study sections. At present Jeff leads three NIH-funded projects. He serves as Associate Editor of the American Journal of Physiology: Renal Physiology, Editor of Comprehensive Physiology: Renal Physiology and a Regular Member of the Kidney Molecular Biology and Genitourinary Organ Development study section at the NIH.
Physiology Annual Picnic
July 12, 2013
The department will be hosting our annual picnic at Squire Valleevue Farm.
Welcome Yinghua Chen
Oct. 1, 2012
The department welcomes Yinghua Chen, who became our Core Facilities Manager on Oct 1st. She received her Ph.D. degree from the University of Alabama in 2009 and then did a postdoctoral fellowship at National Cancer Institute (NCI/NIH) in Bethesda. Her research focus at the NIH was on protein structure determination and protein-protein interactions. Yinghua is the Department’s first Core Facilities Manager, a position that we recently created to organize, streamline, and enhance operations of the Department’s cores and common-usage equipment. These cores include the Protein Expression Purification and Crystallization Core (PEPCC) on the 5th floor of Robbins, as well as the Molecular Biophysics Core on the 6th floor. Her desk will be in the PEPCC.
Dr. Julian Stelzer Awarded First NIH R01 grant
Feb. 1, 2013
Congratulations to Dr. Julian Stelzer on the occasion of his award of an NIH RO1 grant, effective February 1, 2013, for research in the “Functional consequences of FHC mutations in cardiac MyBPC”
Phanindra Velisetty, Sreevatsa V. Chalamalasetti, & Sudha Chakrapani Publish in Journal of Biological Chemistry
Sept. 13, 2012
Congratulations on the publishing of “Conformational transitions underlying pore opening and desensitization in membrane-embedded GLIC”
In Journal of Biological Chemistry
Congratulations to Seong-Ki Lee on the Acceptance of Two Manuscripts!
Jan. 1, 2013
“Substrate specificity of the electrogenic sodium/bicarbonate cotransporter NBCe1-A (SLC4A4, variant A) from humans and rabbits” Lee, S.-K., Boron, W.F., and Parker, M.D. American Journal of Physiology, 2013 (in press)
“Monitoring Ion Activities In and Around Cells Using Ion-Selective Liquid-Membrane Microelectrodes” Lee, S.-K., Boron, W.F., and Parker, M.D. Sensors, 2013 (in press)
DPB Annual Baseball Outing
Aug. 23, 2013
Students, staff, and faculty of the department will take the opportunity to enjoy an evening at Progressive Field. The Indians will be playing the Minnesota Twins, it is Dollar Dog Night, and there will be fireworks.