Dr. Choi has a longstanding commitment to the training of physician-scientists and scientists in lung disease. His passion for mentoring and successful career development of trainees and faculty represents his major mission in academic medicine.
Dr. Choi’s research interest has focused on the regulation and function of cytoprotective molecules in the pathogenesis of lung and vascular tissue injury and repair. His laboratory is focused in delineating the signaling pathways by which cytoprotective molecules impart anti-inflammatory, anti-apoptotic and anti-proliferative effects. He has extensively examined the molecular regulation/signaling pathways and function of anti-oxidant enzymes, in particular heme oxygenase-1 and gaseous molecule carbon monoxide, in variety of in vitro and in vivo models of lung and vascular diseases. Dr. Choi also has interests in genomic approaches in identifying candidates genes important in the pathogenesis of lung diseases, in particular ARDS/sepsis and COPD.