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Journal Club

Cassandra Barone, BS
Cassandra Barone, BS
Feb. 15, 2023 8:45 a.m.
School of Medicine E501
Mentor: Xin Qi, PhD

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JOURNAL CLUB

"Biasing the conformation of ELMO2 reveals that myoblast fusion can be exploited to improve muscle regeneration"

Nature Communications | ( 2022) 13:7077 1; https://doi.org/10.1038/s41467-022-34806-4

https://www.nature.com/articles/s41467-022-34806-4

Viviane Tran1,2, Sarah Nahlé1,3,13, Amélie Robert1,13, Inès Desanlis1,4, Ryan Killoran5, Sophie Ehresmann1,3, Marie-Pier Thibault1, David Barford6, Kodi S. Ravichandran7,8, Martin Sauvageau1,2,3,9, Matthew J. Smith5,10,Marie Kmita1,3,4,11 & Jean-François Côté1,2,3,4,12

1Montreal Clinical Research Institute (IRCM), Montreal, QC H2W 1R7, Canada. 2Department of Biochemistry and Molecular Medicine, Université de Montréal, Montreal,QC H3C 3J7, Canada. 3Molecular Biology Programs, Université deMontréal,Montréal,QC H3T 1J4,Canada. 4Department of Medicine, Université de Montréal, Montreal, QC H3C 3J7, Canada. 5Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, QC H3T 1J4, Canada. 6MRC Laboratory of Molecular Biology, Cambridge CB2 OQH, UK. 7Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville 22908 VA,USA. 8VIB/UGent Inflammation ResearchCentre, BiomedicalMolecular Biology,Ghent University, 9052Ghent, Belgium. 9Department of Biochemistry, McGill University, Montréal,QC H3G 1Y6, Canada. 10Department of Pathology and Cell Biology, Université de Montréal, Montreal, QC H3C 3J7, Canada. 11Department of Experimental Medicine, McGill University, Montréal, QC H3G 2M1, Canada. 12Department of Anatomy and Cell Biology, McGill University, Montréal, QC H3A 0C7, Canada. 13These authors contributed equally: Sarah Nahlé, Amélie Robert. e-mail: jean-francois.cote@ircm.qc.ca