Hormonal control of blood pressure and kidney function; renin-angiotensin-aldosterone system; dopominergic system; renal and vascular paracrine systems; cell and molecular biology of vascular hormones.

Dr. Carey's research is focused on understanding the pathophysiologic mechanisms of hypertension. He is studying the function of dopamine and angiotensin receptors in the kidney, heart and peripheral blood vessels. His laboratory has pioneered the discovery of the function of renal D1-like receptors and angiotensin AT-2 receptors. Current projects involve the role of AT-2 receptors in sodium excretion and hypertension; the interaction of dopamine receptors with angiotensin receptors within the kidney, the role of extracellular renal cyclic GMP in pressure-natriuresis and the role of urinary angiotensinogen as a marker for activation of the intrarenal renin-angiotensin system.

Source: https://med.virginia.edu/faculty/faculty-listing/rmc4c/