Physiology & Biophysics

Research


Isothermal Titration Calorimeter (ITC200)



Manager: Yinghua Chen, PhD
Contact Email: yinghua.chen@case.edu
Contact Phone: 216-368-8962
Availablility: By Appointment

Major Applications:

Characterization of the binding specificity, stoichiometry and thermodynamic profile for molecular interactions of small molecules, proteins, antibodies, nucleic acids, lipids and other biomolecules in a single experiment

Assessment of the effect of molecular structure changes on binding mechanisms

Major Specifications:

Operating temperature range: 2ºC to 80ºC

Response time: 10s

Cell design: 200µL, coin-shaped, fixed-in-place, non-removable, non-reactive

Injection syringe: 40µL, automated, capable of delivering injections as small as 0.1µL

Cell-to-cell heat compensation: Power feedback

 


Manual: ITC-200 Manual
Manufacturer: Microcal
Location: SOM-E603
Required Training: Basic Training
Training Fee: 150.00

Usage Fees:
Microcal ITC200:$30.00 Per hour

Consumable Fees:
Director: Witold K. Surewicz, PhD
Responsible PI: Witold K. Surewicz, PhD
Class: Core Equipment -- PEPCMBC