Physiology & Biophysics

The Protein Expression Purification Crystallization and Molecular Biophysics Core (PEPCMBC)


The PEPCC staff will provide technical assistance to the extent required. Users are requested to acknowledge the PEPCC at department of Physiology and biophysics in resulting publications and presentations and email Dr. Yinghua Chen at yinghua.chen@case.edu about these publications or presentations.

Here are some examples of acknowlegment:

Assistance with XXX measurement from PEPCC at department of Physiology and Biophysics, Case Western Reserve University is appreciated.

If staff design the experiment for you or provide intellectual contribution to a project, please recognize them as an author on the paper.

 

Below are selected publications that used the equipment in our facility:

2017

Lee PW, Shukla S, Wallat, JD, Danda C, Steinmetz NF, Maia JM, Pokorski JK (2017) Biodegradable Viral Nanoparticle/Polymer Implants Prepared via Melt-Processing. ACS Nano. In Press 

2016

Tai W, Zhao G, Sun S, Guo Y, Wang Y, Tao X, Tseng CK, Li F, Jiang S, Du L, Zhou Y (2016) A recombinant receptor-binding domain of MERS-CoV in trimeric form protects human dipeptidyl peptidase 4 (hDPP4) transgenic mice from MERS-CoV infection. Virology, 499, 375-382

Gao Z, Putnam A, Bowers H, Guenther U, Ye X, Kindsfather A, Hilliker A andJankowsky E (2016) Coupling between the DEAD-box RNA helicases Ded1p and eIF4A. eLife 5:e16408

2015

Zhang J, Kiser P, Badiee M, Palczewska G, Dong Z; Golczak M, Tochtrop G and Palczewski K (2015) Molecular pharmacodynamics of emixustat in protection against retinal degeneration. J Clin. Invest. 125, 2781-2794.

Han Z, Zhou Z, Shi X, Wang J, Wu X, Sun D, Chen, Y, Zhu H, Magi-Galluzzi, C, Lu, Z (2015) An EDB fibronectin specific peptide for prostate cancer targeting. Bioconjug Chem. 26(5): 830-838.

Cao P, Su Z, Leon A, and Advincula R (2015) Photoswithable nanocarrier with reversible encapsulation properties. MacroLetters 4, 58-62.

2014

Mehrotra N, Nichols J, and Ramachandran R (2014). Alternate pleckstrin homology domain orientations regulate dynamin-catalyzed membrane fission. Mol Biol Cell 25, 879-890.

Macdonalda PJ, Stepanyantsa N, Mehrotraa N, Mears JA, Qi X, Sesakid H, and Ramachandrana R (2014). A dimeric equilibrium intermediate nucleates Drp1 reassembly on mitochondrial membranes for fission. Mol Biol Cell 25, 1905-1915.

2013

Ruschak AM, Rose JD, Coughlin MP, Religa TL (2013) Engineered solubility tag for solution NMR of proteins. Protein Sci 22, 1646-1654